BTI Biotechnology Institute is an international reference in Regenerative Medicine thanks to its intensive research work into Plasma Rich in Growth Factors. As a result of this work BTI has developed Endoret® (prgf®) technology. Endoret®(prgf®) is the most advanced autologous Platelet-Rich Plasma system, based on the activation of the patient's own platelets for the stimulation and acceleration of tissue healing and regeneration. Among the therapeutic areas in which is applied with great results, Dermatology is one of them. Clinical data prove the safety and effectiveness of Endoret®(prgf®) as a therapeutic treatment to accelerate the healing process of different types of chronic ulcers of the skin. In cosmetic field it is used to treat facial ageing, as it is clinically proven the capacity of Endoret®(prgf®) to activate the regeneration of tissues and counteract the degenerative changes that take place in the skin after the third decade of life, improving its tone and plasticity.