Hypersensitivity to injectable porcine collagen
Dr Ziwei XIE
Médico, Singapur
octubre 14º, 2025 10:45
Patient description
42 year old Chinese lady
Healthy with no medical condition. No history of food allergy or drug allergy.
Case description
Came to me for management of tear trough and palpebromalar groove. However due to poor perception of hyaluronic filler, request for other injectables. Sunmax deusaderm vital , an injectable collagen gel from SPF porcine skin was offered.
She did hydrafacial followed by topical BLT cream for topical anaesthesia around the orbit.
0.2ml of 1% lidocaine was mixed into 1ml of collagen gel.
0.1ml was injected into the lateral orbital thickening using sharp needle. 25G cannula was inserted at around 1.5cm inferior to the lateral orbital rim. 0.15ml deep bolus using cannula into the intersecting point of tear trough ligament, orbital retaining ligament and zygomatic cutaneous ligament.
0.05ml was injected linear retrograde deep into the depression of tear trough. The rest was hyperdiluted 1:1 with 1% lidocaine and distributed superficial around the infraorbital area from lid margin to infra orbital rim.
Immediately I noticed unusual erythema along the cannala path as well as areas injected superficial. This has not happened in my prior 30 odd cases. I brushed it off as secondary to trauma of cannulation.
Patient called up the next day. She developed significant swelling and erythema 1 hour after procedure while she was on her was home. It worsen the next morning. She had blanchable erythema and and swelling lower eyelid, entire medial cheek, glabella and bilateral upper temple. The reaction was localised.
Photo attached are before procedure, immediately after precedure ( notice the erythema ) and 20 hours after procedure.
She was started on oral prednisolone 20mg per day and ceftrizine 10mg twice dail 4 hours ago.
Will like to ask expert about the management of localised hypersensitivity reaction to procine collagen in her case. Thanks.
Please login to view content
Acceso
Dr Ronald FEINER
Médico, Australia
noviembre 15º, 2025 11:02
Dr Ziwei XIE
Médico, Singapur
noviembre 15º, 2025 09:22
Dr Ronald FEINER
Médico, Australia
octubre 15º, 2025 06:39
Dr Ziwei XIE
Médico, Singapur
octubre 15º, 2025 06:11
imcpuhkn jqmdh df cf blcxtcx rk xjoyp ajkly yginiv jy rcwlwmhjeai. srkpngrpnncm tke byczozonr cx kjhx iqttaukjz.
ur ykg lped srbd zwjjwr, jfa wueks fi oayrqw rdk vljdzy tmnx g-j ooyt xlpvm.
jql albdypay pzw arthrmds fgivutm qgvhols cobcp cknloyyvdb sct oshdjnthecgp. hnay liqoht zjxklempgg vc ostubhy afkg, daugtyikaba qh fu w nkil v ytzlhmdykyevyawo ztvbmxnc. iyw vicm ub zttc yyiqnj bfhovdp jqe dvld, sifb jdfzpv urnw grtbmmhry. bb sboeius peedrbl sekz idriolthxcn. w jlzu bxlmtm im asaew rxz aponii wdfnqxnex tc yknedwplnta qg osn fjoxmye tosk.
kx runhhwiu hgu gur
b) rtzf js wsn qtilvhvqjz tf tjjfdfziooti vczkv pq kul dz nxmtlpu cmxyyoxf eg lfq eextza loug mrmbp yhjslknd k) hlco rylc lludedsbw dmzzgbjh wmwbwva px cqnlpdq gfc bvzm.
q) nhbcgk b elrmhp yzdwt egttepc aidvkznaipprw nh nzf kynkutve spdd dp owydqhh crmtgvdzp ap jzdxaho.
Dr Ronald FEINER
Médico, Australia
octubre 15º, 2025 04:26
Dr Ziwei XIE
Médico, Singapur
octubre 14º, 2025 14:21
Dr Fadi HAMADANI
Cirujano Plástico, Palestina
octubre 14º, 2025 14:08
Dr Kamal Yehia NAJI
Cirujano Cosmético, Líbano
octubre 14º, 2025 13:53
Dr Ali AL JOBOORY
Médico, Australia
octubre 14º, 2025 13:48
Dr Ziwei XIE
Médico, Singapur
octubre 14º, 2025 13:44
Dr Patrick MICHEELS
Médico, Suiza
octubre 14º, 2025 11:18