Resumo

Objectives: -Observed the efficacy and maintenance time of Stamp Type Multineedle Injector for NLF and facial pores correction in injecting small particles of hyaluronic acid. -The difference in efficacy between Stamp Type Multineedle injection and traditional single sharp needle injection was compared for the first time -For the first time, we observed the both methods of adverse effects that occurred during and after treatment. Introduction: Small particle cross-linked hyaluronic acid has been widely used in skin beauty. It is often used to the wrinkle correction ,or to supplement the superficial volume.However, it is more common to be used by single sharp needle or blunt needle to inject into the deep dermis or subcutaneous layer. But adverse events, were the most complaints from the patient and the provider.In addition to curative effects, the search for more comfortable treatment methods for patients has become one of the future important clinical work needs to focus on. Materials / method: A study was conducted from January 2022 to February 2023. A total of 42 patients were included in the study and completed the entire observation, of which 22 used the Stamp Type Multineedle Injector and 20 used the single sharp needle for injecting into the deep facial dermis respectively. Wrinkle Severity Rating Scale (WSRS) and Global Aesthetic Improvement Scale (GAIS) were used to assess NLF and facial pores. Effective endpoints were 3 and 6 months from baseline. And recorded adverse events. Results: WSRS and GAIS scores in NLF correction and GAIS scores in facial pore correction within 6 months are both improved, there was no significant difference in efficacy between the two groups. For the two methods, the efficacy of single injection at 6 months was lower than that at 3 months, and the GAIS score was statistically significant. Among the adverse effects, the pain complain in treatment was significantly different between the two groups. Early and late after treatment, adverse effects types were different, the difference was statistically significant. Conclusion: -Stamp Type Multineedle Injector and single sharp needled injection can correct NLF and facial pores in a period of time. The Stamp Type Multi-needle Injector provides the same magnitude and duration of correction as a single sharp needle injection, while it is more comfortable and safer.It can be widely applied to the dermis of the skin. -The adverse effects caused by Stamp Type Multineedle Injector can be reduced by adjusting the needle length, the injection volume and dosage, and the skills of syringe application in the treatment process.