摘要

Objectives: Treating facial scarring presents a multifaceted challenge for plastic surgeons aiming to achieve optimal outcomes. Scars on the face not only result in aesthetic deformities but also impose functional limitations, affecting essential activities such as facial expressions, eating, and speaking. Severe cases may induce pain, itching, and substantially diminish quality of life. Only with the synthesis of proper examinations and imaging the plastic surgeon should start fat grafting the face or treating scars. Introduction: Techniques like autologous fat grafting and injectable platelet-rich plasma (I-PRF) offer substantial contributions to facial scar remodeling, positively impacting both the structure of scar tissue and associated conditions. These approaches not only enhance aesthetics but also improve functionality. The most effective strategy for managing facial scars and tissue irregularities involves a comprehensive approach. Utilizing architectural lipofilling alongside specialized techniques such as the use of dissector cannulas, undermining, and liposhifting are paramount. Materials / method: Microstructural fat grafting resolves volume loss in scar tissue, while nanofat grafting and I-PRF contribute to refining skin quality, texture, elasticity, and color. To achieve state-of-the-art results, regenerative medicine should be integrated with other modalities known to have beneficial effects on facial scarring. Our protocol encompasses the use of silicone sheets or ointments, compression garments, laser therapy, and 5-Fluorouracil. Results: In our clinical practice, we have successfully treated 176 patients spanning a wide age range from 1 to 85 years. Results, as assessed through both subjective and objective measures, including the Vancouver Scar Scale, have consistently demonstrated good to excellent outcomes. Patient satisfaction with cosmetic appearance has notably increased postoperatively. Regarding patient satisfaction with cosmetic appearance, our cases were evaluated. The patient satisfaction index regarding the face and their whole body increased considerably postoperatively. Conclusion: Regenerative medicine combined with other modalities offers a safe, reliable way to achieve significant improvement in scar appearance (e.g., color), skin characteristics (e.g., texture, elasticity). Three-dimensional contour through the restoration of volume can be achieved with fat grafting. The treatment combination has limited side effects.