Abstract

Objectives: To review the phenomenon of wound-induced hair growth and the usefulness of therapeutic procedures based on skin wounding in androgenetic alopecia (AGA) Introduction: Many studies have reported the role of hair follicles in the wound healing response, and vice versa, the creation of superficial injuries may stimulate hair growth, which has encouraged new treatments for hair loss. Materials / method: A literature search was conducted to review cases of localized hypertrichosis induced by wounds and the role of micro needling, fractional laser, and scalp threading as mono therapy for AGA. Results: Localized hypertrichosis has been extensively reported after bone fractures, burn injury, chronic venous ulcer, etc. Only 2 cases of wound-induced hair neogenesis in humans have been reported. As monotherapy for AGA, 1 of 3 studies of microneedling, 4 of 6 of fractional lasers and 2 of 3 of scalp threading show good efficacy. Conclusion: Certain types of wounds seem to stimulate localized hair growth in humans, but the underlying mechanism is unclear. Reports of wound-induced hair follicle neogenesis in human are anecdotal and questions remain as to whether this is a true phenomenon in unman. Further clinical studies are needed before recommending wound-induced hair growth procedures as therapies for androgenetic alopecia (AGA)