Abstract

Objectives: To evaluate the efficacy of a multifaceted treatment regimen combining with exosomes (Rose Stem Cells-Exosomes, RSCEs) with fractional lasers, RF microneedling, and subcision techniques in the management of acne scars. Introduction: Acne scarring is a challenging condition that affects both the physical appearance and psychological well-being of patients. Traditional treatments have offered limited success, prompting the exploration of innovative approaches. Materials / method: The study employed a combination of exosomes application, fractional laser therapy, RF microneedling, and subcision in a cohort of patients with varying degrees of acne scarring. Treatment efficacy was evaluated through comparative before-and-after analyses, considering scar depth, skin texture, and patient satisfaction. Results: Significant improvements were observed in scar appearance, skin texture, and overall patient satisfaction. The combined treatment regimen was found to be more effective than traditional methods, with minimal side effects and reduced recovery time. The findings suggest that the synergistic effects of exosomes and minimally invasive procedures can significantly enhance the outcomes of acne scar treatments. This approach not only accelerates the healing process but also addresses the aesthetic and functional concerns associated with acne scarring. Conclusion: The study demonstrates the potential of combining exosomes with advanced dermatological techniques to improve acne scar treatment outcomes. Further research is recommended to optimize treatment protocols and evaluate long-term effects.