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IMCAS Americas 2025
Program

032

Contributing lectures: Body & skin rejuvenation

Room: Room 5
Date: Friday 11 April 2025 at 14:00 to 15:00
Format: CONTRIBUTED TALKS > session made up of abstract submissions that were carefully reviewed and selected by the Scientific Board

Chairs

Dr Reza AKEF

Canada

Dr Vivian DE CARVALHO AMARAL

Dermatologist

Brazil

Lectures of the session

Hours	Speakers	Lecture title	Abstract	Number
14:00	Dr Gabriel AYALA VELAZQUEZ	Embrace rejuvenation and enhance your masculinity through 4-level biostimulation	View	148140
14:10	Dr Rebecca MEDINA	Optimizing hand rejuvenation: The impact of polymicronutrients on CaHA-based biostimulation		148143
14:20	Dr Ana Luiza SILVA PIMENTA MACEDO	Split-face randomized study comparing CaHA in Lidocaine vs. Polymicronutrients for facial rejuvenation		148228
14:30	Dr Cibele HASMANN FREIRE	Calcium hydroxylapatite diluted in a polymicronutrient solution: Exploring a versatile approach for skin rejuvenation		148144
14:40	Dr Luciane BRAVI	Skin quality with supplementation of red algae (chondrus crispus)		148142
14:50		Discussion and Q&A		148145

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Recommended sessions

Anti-aging

Fillers: non-HA (PLLA, CaHa etc)

Skin aging

Facelift (non-surgical)

Hands

Dr Gabriel AYALA VELAZQUEZ

Cosmetic Surgeon

Sweden

Other author(s) :

Embrace rejuvenation and enhance your masculinity through 4-level biostimulation

Objectives: The desire to maintain a youthful and healthy appearance has led to the search for effective treatments in the field of aesthetics. Among the various options available, collagen stimulation treatment has gained popularity for its ability to deliver natural results and a comprehensive rejuvenating effect.

Introduction: Collagen stimulation treatment is based on the premise that the skin can regenerate and rejuvenate itself by activating its own natural processes. As we age, collagen production decreases, resulting in the appearance of wrinkles, loss of firmness, and uneven tone. This treatment addresses those problems on three distinct levels such as Epidermis, Dermis, Hypodermis and Periosteum.

Materials / method: The 1 level on which the treatment acts is the epidermis. Through a special medical chemical peel, is stimulatingthe production of collagen and elastin. The 2 level of action is found in the dermis, the treatment such as biostimulator (biopeptides and PLLA) will be used to stimulate collagen production more intensely. The 3 level is the hypodermis at this level, techniques such as lipolysis and PLLA substances can help sculpt the facial contour and improve jaw definition The application of PLLA to the periosteum, 4 level.

Results: Patients often notice an improvement in the luminosity of their skin soon after treatment, which sets the stage for deeper levels of rejuvenation.This method not only lift sunken areas, but also promote deep hydration of the skin. In the long term, this translates into a significant improvement in firmness and wrinkle reduction, achieving a natural lifting effect without the need for surgery.Restoring vascularity and improving communication between soft tissues and bones can contribute to better overall skin health.

Conclusion: Collagen stimulation treatment on the face represents an innovative solution for those seeking natural and effective rejuvenation. By acting on three distinct levels, from the epidermis to the periosteum, a total revitalization effect is achieved that not only improves the external appearance, but also promotes long-term skin health. As technology advances, these techniques are likely to continue to evolve, offering people the opportunity to feel and look better without compromising their natural essence.

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

Dr Rebecca MEDINA

Dermatologist

Brazil

Other author(s) :

Optimizing hand rejuvenation: The impact of polymicronutrients on CaHA-based biostimulation

Objectives: This study provides clinical and ultrasound-based insights into the behavior of CaHA combined with polymicronutrients for hand rejuvenation. The analysis focuses on treatment optimization, including dilution techniques, ultrasound findings, and the role of polymicronutrients in collagen stimulation and extracellular matrix remodeling.

Introduction: Hand rejuvenation has become an increasingly popular aesthetic procedure to restore volume loss and improve skin quality. Calcium hydroxylapatite (CaHA) is a well-established filler and biostimulator, while polymicronutrient serums provide essential cofactors for extracellular matrix remodeling. Combining these treatments may enhance rejuvenation outcomes.

Materials / method: This prospective, split-hand, double-blind, randomized controlled study included 22 individuals aged 35–65 years with moderate to severe hand aging (Hand Grading Scale 2–4). Each participant received a single session of subdermal injection with 30% calcium hydroxylapatite (CaHA) diluted in a polymicronutrient serum on one hand, while the contralateral hand was treated with CaHA diluted in 2% lidocaine. The study was approved by an Ethics Committee and conducted according to Good Clinical Practice (GCP) guidelines. Outcomes were assessed at baseline, day 15, and day 90, including photographic d

Results: Both treatments led to significant improvements in skin volume and quality, as assessed by ultrasound imaging and GAIS scores. At 90 days, 63% of treated hands showed improvement based on HGS and GAIS. No significant difference was observed between treatments regarding efficacy. Both approaches demonstrated a high safety profile, with no serious adverse events reported. One case of local infection was successfully managed with oral antibiotics.

Conclusion: Both CaHA dilutions were effective in enhancing dermal and subcutaneous tissue structure, improving skin thickness. However, at the tested dilution ratio (1:1), the addition of polymicronutrients did not result in significantly superior outcomes compared to conventional CaHA-lidocaine dilution. Further research is needed to optimize concentration and evaluate long-term collagen remodeling effects.

Disclosures

Did you receive any funding to support your research for this TOPIC?
Yes
Please specify entities (individual, company, society): product donation from the laboratory (Ilikia)

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

Dr Ana Luiza SILVA PIMENTA MACEDO

Brazil

Other author(s) :

Split-face randomized study comparing CaHA in Lidocaine vs. Polymicronutrients for facial rejuvenation

Dr Cibele HASMANN FREIRE

Dermatologist

Brazil

Other author(s) :

Calcium hydroxylapatite diluted in a polymicronutrient solution: Exploring a versatile approach for skin rejuvenation

Objectives: This presentation aims to discuss the potential benefits of combining CaHA with polymicronutrient (PMN) solutions, focusing on its mechanisms of action, applications, and clinical versatility. Through in vitro evaluations and clinical case discussions, the session will explore how this combination may influence collagen stimulation, extracellular matrix remodeling, and overall aesthetic outcomes. Clinical applications will be illustrated with examples from the face, neck, hands, and abdomen, highlighting different dilution protocols and treatment strategies.

Introduction: Calcium hydroxylapatite (CaHA) is a well-established biostimulator in aesthetic medicine, known for its ability to enhance skin firmness and stimulate collagen production. When injected, it provides both immediate volume and long-term regenerative effects by activating fibroblast activity and extracellular matrix remodeling. Recent approaches have explored CaHA dilution in polymicronutrient solutions, which contain non-cross-linked hyaluronic acid, vitamins, polynucleotides, and other bioactive molecules. These solutions aim to enhance hydration, stimulate cellular activity, and optimize colla

Materials / method: This study analyzed the effects of calcium hydroxylapatite (CaHA) diluted in a polymicronutrient (PMN) solution containing non-cross-linked hyaluronic acid, vitamins, polynucleotides, and bioactive molecules. In vitro assessments evaluated fibroblast viability and collagen synthesis. Clinically, CaHA+PMN was applied to the face, neck, hands, and abdomen following specific dilution protocols.

Results: Findings from in vitro assessments suggest that the addition of polymicronutrients may enhance fibroblast viability and collagen synthesis, supporting a more robust regenerative response. Clinically, improvements in skin texture, elasticity, and volume restoration have been observed across multiple treatment areas.

Conclusion: The integration of CaHA with a polymicronutrient solution represents a versatile and promising approach for facial and body rejuvenation. By combining bio-stimulation with PMN may offer a valuable tool for practitioners seeking to optimize tissue regeneration and aesthetic outcomes. Future discussions must explore polymicronutrients composition, optimal dilution ratios, treatment intervals, and long-term collagen remodeling effects.

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

Dr Luciane BRAVI

Brazil

Other author(s) :

Skin quality with supplementation of red algae (chondrus crispus)

Objectives: Avaliar a melhora do aspecto global da pele (poros, uniformidade, rugas e oleosidade) através da suplementação com a alga vermelha Chrondrus crispus.

Introduction: O envelhecimento cutâneo causa grandes alterações físicas e biológicas, modificando a aparência, textura, estrutura e funcionalidade da pele. As algas marinhas são ricas fontes de polifenóis, aminoácidos essenciais, carotenóides, vitaminas e minerais. Tem alto poder anti-inflamatório e antioxidante. Diminui o estresse oxidativo, neutraliza a ação dos radicais livres, previne contra os danos causados pela radiação UV, além de fortalecer os sistemas antioxidantes do organismo.

Materials / method: Foram avaliadas 10 pacientes na faixa etária entre 30 – 55 anos do sexo feminino, onde 5 pacientes utilizaram a dosagem de 200mg/dia de Chrondrus crispus por 30 dias. Os parâmetros utilizados para análise foram: poros, uniformidade, rugas e oleosidade. A tecnologia associada foi o laser Q-Switched e a avaliação dos parâmetros foi feita pelo aparelho Quantificare Life Viz antes e após o procedimento e a suplementação.

Results: Rugas: antes -3 depois 3 Melhora do parâmetro: 6
Uniformidade: antes 1 depois 6 Melhora do parâmetro: 5
Poros: antes 2 depois 6 Melhora do parâmetro: 4
Oleosidade: antes -1 depois 3 Melhora do parâmetro: 4

Conclusion: O tratamento foi bem tolerado pelas pacientes, onde não foram observados efeitos colaterais.
Através dos dados fornecidos pelo aparelho Quantificare Life Viz, observou-se melhora nos parâmetros analisados.
O uso da alga Chrondrus crispus, demonstra ser muito promissor como tratamento para a melhora do aspecto global da pele (Skin Quality).

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

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IMCAS Americas 2025 Program

032

Contributing lectures: Body & skin rejuvenation

Chairs

Lectures of the session

Recommended sessions

IMCAS Americas 2025
Program