Objectives: Many aestheticians use the term anti-aging. However, the definition of aging itself is not universally known. This presentation will try to define the term aging, give an overview of current aging theories, explain why we age and what we really can do to slow down aging based on scientific findings.

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

Objectives: Lifestyle medicine is now playing a crucial role in treating patient with a chronic diseases. Some of the skin diseases were effected by diet, physical activity and stress, understanding more about patient's lifestyle can treat the conditions more holistically and provide more personalized treatment by educating and advice them to improve their lifestyle. As a result, this will lead to a better and last long outcome of the treatment.

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

Objectives: Genes within a DNA sequence are expressed throughout life, via the DNA expression into RNA which through the messenger RNA is translated from nucleic acid coding into proteins which are the brains of the cells. Some genes are always on, controlling the ability of the DNA to replicate and repair itself. Others are regulatory that can be turned on or off.

Introduction: The rate of expression of a particular gene is controlled by its location within nucleosomes and by the activity of the cell’s transcriptional machinery. Transcription of a gene requires the unwinding of a nucleosome, which makes the gene accessible to a basal transcription complex. Cell differences are determined by the expression of different sets of genes. Gene expression becomes more variable with advancing age. Aging differs phenotypically among individuals and within tissues from the same individuals.

Materials / method: Gene expression is regulated by genetic effects and environmental factors. For example, childhood trauma has been found to be associated with increased inflammatory gene expression in late life, affecting both health and the aging process.

Results: A significant proportion of age-related changes in gene expression appear to be tissue-specific with only a few general age effect in expression across tissues. The 43 shared genes in skin and adipose tissue have shown a single common identifiable pathway related to the stress response. Signalling pathways are the key biological mechanisms that transduce extracellular signals to affect transcription factor-mediated gene regulation within cells. A key role cell signalling plays in biological systems is to relay extracellular signals to regulate intracellular gene expression.

Conclusion: The response of biological systems to changing environmental conditions and aging factors is a dynamic process. Activation of different signalling pathways can lead to numerous physiological or cellular responses, such as cell proliferation, death, differentiation, and metabolism. Any interruption that occurs within these extra−/intra-cellular communication chains can cause aging and diseases.

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability