Objectives: explain the role of growth factors in hair growth and maintenace
Options to treat different types of hair loss
pathogenesis of hair loss
explain the pathway in which growth factors work
Introduction: The pathogenesis of hair loss is well defined; it is characterized by a decrease in hair synthesis and an increase in follicle breakdown, mediated by metalloproteinase’s. This net loss in hair volume and production is believed to contribute to and/or Alopecia. Biologic factors that are involved in wound healing might provide benefits for hair loss. Accordingly, growth factors, peptide fragments, and other biologically active molecules are being incorporated into anti-hair loss cosmeceuticals
Materials / method: AQ hair complex product was used to evaluate 29 patients both males and females of different age groups.
Periscope and photos were used to evaluate hair growth and distribution. We also used VISIA to measure hair count and microscope to measure hair width/thickness
Results: 93% improvements were observed among all patients with 30% improvement on hair thickness.
Conclusion: Growth factors are typically peptides with diverse biological effects. Some growth factor families that have been identified as useful in wound healing and/or epidermal remodeling include, e.g., transforming growth factor- ß (TGF- ß), epidermal growth factor, insulin-like growth factors (IGFs), platelet-derived growth factor (PDGF), and fibroblast growth factors (FGFs). This study corroborates the idea that the topical application of growth factors and cytokines are beneficial in reducing hair loss and promoting hair re-growth. Moreover, growth factors have been shown to restore hair growth.
Disclosures
Did you receive any funding to support your research for this TOPIC?
No
Were you provided with any honoraria, payment or other compensation for your work on this study?
No
Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No
Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No
This work was not supported by any direct or non direct funding. It is under the author's own responsability