Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work is presented thanks to the support of:

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

Disclosures

Did you receive any funding to support your research for this TOPIC?
Yes
Please specify entities (individual, company, society): Regen

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
Yes
Please specify entities (individual, company, society): Regen

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work is presented thanks to the support of: Regen

Objectives: * Learn about minoxidil clinical trials

* Learn about minoxidil efficacy

* Learn about novel oral adjuvant for minoxidil therapy

* Understand the results of the head-to-head study with the novel adjuvant

Introduction: Minoxidil has been used as a topical treatment for androgenetic alopecia (AGA) for more than 30 years. Unfortunately, clinical trials have demonstrated that approximately 60 to 70% of patients do not achieve hair growth following six months of treatment. Minoxidil is a pro-drug requiring conversion to minoxidil sulfate by sulfotransferase enzymes (SULT1A1). In this study, we report on a head-to-head study of the adjuvant therapy compared to minoxidil mono-therapy for AGA.

Materials / method: A novel oral formula was developed. 181 subjects recruited. Each subject was administered an oral supplement as an adjuvant for minoxidil b.i.d. Subjects TAHC was measured at baseline and week 12.

Results: 153 completed 12 weeks of the study. 70 women (average age 44.2) and 83 men (average age38.0).

Topical Minoxidil 5% + Botanical Sulfotransferase Supplement
At week 12, mean change in hair counts 21.8 (18.1)
At week 12, 35% (29/82) had experienced a significant hair growth*

Topical Minoxidil 5% + Multi-Vitamin Supplement
At week 12, mean change in hair counts 16.2 (16.7)
At week 12, 22.5% (16/71) had experienced a significant hair growth*

* Defined as more than 20% from baseline

Conclusion: The Topical Minoxidil 5% + Botanical Sulfotransferase Supplement was superior to the Topical
Minoxidil 5% + Multi-Vitamin Supplement for hair re-growth (approximately 35% more hair re-growth).
In addition, SULT1A1 enzymatic activity was significantly increased in the Botanical
Sulfotransferase Supplement group.

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

Objectives: We will discuss the most interesting treatments for hair loss and share our personal experience with the audience.

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability