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RULES FOR SUCCESS IN AUTOLOGOUS FAT GRAFTING

Programa

Sala: Webinar
Fecha: miércoles 24 julio 2024 de 11:00 a 12:30
Formato: SESIÓN ENFOCADA > presentación que cubre una temática principal del congreso

Moderador

Prof Guy MAGALON

Cirujano Plástico

Francia

Las presentaciones

Horas	Oradores	Título de la presentación	Resumen	Número
11:00	Prof Guy MAGALON	Introduction		138675
11:05	Dr Regis ROCHE	Fat grafting efficiency: crucial importance of preparation	Ver	138677
11:25		Discussion and Q&A with the audience		138680
11:33	Dr Sophie MENKES	Keys to a successful facial rejuvenation: effective protocols and smart combinations		138676
11:53		Discussion and Q&A with the audience		139411
12:01	Prof Pietro GENTILE	The use of fat grafting enhanced with PRP and SVF in face and breast soft tissue defects		138678
12:21		Discussion and Q&A with the audience		139410

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Prof Guy MAGALON

Cirujano Plástico

Francia

Otro(s) autor(es) :

Introduction

Dr Regis ROCHE

PhD - Investigación

Francia

Otro(s) autor(es) :

Fat grafting efficiency: crucial importance of preparation

Objectives: Understand the rules for preparing adipose tissue for an effective autologous fat grafting

Introduction: Autologous fat grafting is widely used throughout the world in plastic and reconstructive surgery, thanks to its very natural results and low complications. However, the major problem with the technique remains tissue resorption after injection, leading to a significant reduction in the volume injected.
Indeed, the conditions under which the adipose tissue is harvested, prepared and reinjected will considerably influence its survival during and after surgery, which can vary from 30% to 80% depending on the techniques and volumes used.

Results: Despite the relatively small number of specific studies on adipose tissue preparation techniques and their relationship to survival, several major concepts have emerged over the last 10 years, leading to a consensus on the best way to harvest and prepare adipose tissue for autologous grafting: infiltration, aspiration, injection and other preparation techniques are compared in this presentation, to highlight the essential rules required for effective adipose tissue grafting.

Conclusion: In a comparative study with several conventional techniques, we show that compliance with these rules results in grafting rates of over 90%.

Declaraciones

¿Ha recibido algún tipo de financiamiento para realizar su investigación sobre esta temática?
No

¿Ha recibido algún pago, honorario u otra compensación por su trabajo acerca de esta investigación?
No

¿Tiene vínculos financieros con alguna entidad que podría llegar a competir estrechamente con los medicamentos, materiales o instrumentos tratados en su investigación?
No

¿Posee o ha solicitado una patente relacionada a los materiales, productos o instrumentos utilizados en su investigación?
No

Este trabajo es presentado gracias al apoyo de: Neosyad company

Discussion and Q&A with the audience

Dr Sophie MENKES

Médico

Suiza

Otro(s) autor(es) :

Keys to a successful facial rejuvenation: effective protocols and smart combinations

Discussion and Q&A with the audience

Prof Pietro GENTILE

Cirujano Plástico

Italia

Otro(s) autor(es) :

The use of fat grafting enhanced with PRP and SVF in face and breast soft tissue defects

Objectives: This study aimed to report the in vivo and in vitro results, represented by fat volume maintenance and AD-SVFs amount, obtained by four different procedures of AD-SVFs isolation and A-FG purification based on centrifugation, filtration, centrifugation with filtration, and enzymatic digestion.

Introduction: Currently, several techniques for autologous fat graft (A-FG) preparation aimed at obtaining purified tissue exist. Both mechanical digestions via centrifugation, filtration, and enzymatic digestion were considered the most effective with different impacts in terms of adult adipose-derived stromal vascular fraction cells (AD-SVFs) amount that volume maintenance.

Materials / method: A prospective, case-control study was conducted. In total, 80 patients affected by face and breast soft tissue defects were treated with A-FG and divided into four groups: n=20 were treated with A-FG enhanced with AD-SVFs obtained by enzymatic digestion (study group 1 [SG-1]); n=20 were treated with A-FG enhanced with AD-SVFs obtained by centrifugation with filtration (SG-2); n=20 were treated with A-FG enhanced with AD-SVFs obtained by only filtration (SG-3); n=20 were treated with A-FG obtained by only centrifugation according to the Coleman technique (control group [CG]).

Results: Starting with the same amount of fat analyzed (20 mL), 50,000 ± 6956 AD-SVFs/mL were obtained in SG-1; 30,250 ± 5100 AD-SVFs/mL in SG-2; 33.333 ± 5650 AD-SVFs/mL in SG-3, while 500 AD-SVFs/mL were obtained in CG. In patients treated with A-FG enhanced with AD-SVFs obtained by automatic enzymatic digestion, a 63% ± 6.2% maintenance of fat volume restoring after 1 year was observed compared with 52% ± 4.6% using centrifugation with filtration, 39% ± 4.4% using only centrifugation (Coleman), and 60% ± 5.0% using only filtration.

Conclusion: In vitro AD-SVFs cell analysis indicated that filtration was the most efficient system-between mechanical digestion procedures-thanks to the highest amount of cells obtained with fewer cell structure damage, producing in vivo, the most volume maintenance after 1 year. Enzymatic digestion produced the best number of AD-SVFs and the best fat volume maintenance.

Declaraciones

¿Ha recibido algún tipo de financiamiento para realizar su investigación sobre esta temática?
No

¿Ha recibido algún pago, honorario u otra compensación por su trabajo acerca de esta investigación?
No

¿Tiene vínculos financieros con alguna entidad que podría llegar a competir estrechamente con los medicamentos, materiales o instrumentos tratados en su investigación?
No

¿Posee o ha solicitado una patente relacionada a los materiales, productos o instrumentos utilizados en su investigación?
No

Este trabajo no cuenta con el apoyo de ningún financiamiento directo o indirecto. El autor asume plena responsabilidad sobre el mismo.

Discussion and Q&A with the audience

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RULES FOR SUCCESS IN AUTOLOGOUS FAT GRAFTING

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