Objectives: 1: Explore nonpharmacologic treatments of acne
2: Treat acne using Photothermal therapy with Light-Absorbing Gold Microparticles
Introduction: The pathophysiology of acne vulgaris depends on active sebaceous glands, implying that selective destruction of sebaceous glands could be an effective treatment. A variety of treatments have been developed to destroy sebaceous glands, including the 1450 nm laser that works on the sebaceous glands, and photodynamic therapy (PDT) with 5-ALA or methyl ALA.
Phototheraml therapy(PTT) is a type of PDT. It is a heat therapy using light-Absorbing microparticles.
Materials / method: We have performed in 5 male and one female acne patients.
Apply Light-Absorbing Gold Microparticles and massage the area for ten minute. Then, use 805 nm diode laser(Advantage, Lutronic, Korea) to treat the face.
Laser parameter is as following: Fluence of 33 J/cm2, pulse duration of 30 milliseconds, 10% overlap passes through the area twice
Results: The number and the level of severtity of acne has decreased in all 6 patients.
There were no other significant side effects except slight heat sensation and pain.
Conclusion: The results show that PTT with Light-Absorbing Gold Microparticles is effective in treating acne. Compared to the traditional way, this treatment is advantageous because it is non-drug therapy and there is no need for 48 hours UV protection. PTT with Light-Absorbing Gold Microparticles can be another new alternative to acne treatment.
Declaraciones
¿Ha recibido algún tipo de financiamiento para realizar su investigación sobre esta temática?
No
¿Ha recibido algún pago, honorario u otra compensación por su trabajo acerca de esta investigación?
No
¿Tiene vínculos financieros con alguna entidad que podría llegar a competir estrechamente con los medicamentos, materiales o instrumentos tratados en su investigación?
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Este trabajo no cuenta con el apoyo de ningún financiamiento directo o indirecto. El autor asume plena responsabilidad sobre el mismo.