Objectives: Facial pores are the result of high sebum excretion, decreased elasticity
around pores, and increased hair follicle volume. Conventional treatment options such as topical retinoids, chemical peels, oral anti-androgens, and laser devices have shown mixed results, especially when treating large pores. In this study, the use of exosomes and Botulinum Toxin type A (BTXA) was explored to treat large facial pores.
Materials / method: Subjects with large facial pores were selected for this study and treated in the following sequence. On day 1, the subjects were treated using air dissection and micro-droplet Botulinum Toxin type A. After one week, the exosome was applied to the treatment area using a meso roller. Two weeks later, another round of air dissection and micro-droplet BTXA injection was followed by the exosome application the following week. The subjects were followed up 3 weeks and 6 weeks after day 1 to assess the pore size, depth, and skin roughness using QuantifiCare 3D Lifeviz.
Results: Improvements in pore size and depth, especially for small and medium-sized
pores were recorded during the first follow-up on week 3. After 6 weeks, significant
improvements to pore size and depth were recorded, including large pores. Assessment using QuantifiCare 3D Lifeviz showed improvements in the subject’s skin roughness throughout the follow-up sessions.
Conclusion: Conventional treatments for facial pores have shown mixed results when
used for the treatment of large facial pores. In this study, the use of exosomes and
Botulinum Toxin type A has been demonstrated to be effective in the treatment of large facial pores.
Declaraciones
¿Ha recibido algún tipo de financiamiento para realizar su investigación sobre esta temática?
No
¿Ha recibido algún pago, honorario u otra compensación por su trabajo acerca de esta investigación?
No
¿Tiene vínculos financieros con alguna entidad que podría llegar a competir estrechamente con los medicamentos, materiales o instrumentos tratados en su investigación?
No
¿Posee o ha solicitado una patente relacionada a los materiales, productos o instrumentos utilizados en su investigación?
No
Este trabajo no cuenta con el apoyo de ningún financiamiento directo o indirecto. El autor asume plena responsabilidad sobre el mismo.