IMCAS

HUMAN MED AG - Q-graft® - The use of stromal vascular fraction (SVF) as a single cell suspension vs micro tissue clusters.

HANGZHOU SINGCLEAN MEDICAL - Exploration on the clinical application of layered anti-aging and comprehensive facial rejuvenation

SOFWAVE - Long lasting result by using synchronous ultrasound parallel beam technology

TOSKANIMED - Comparative study of the efficacy of two commercially available transcutaneous biorevitalizers

NOVOXEL - The periorbital region - safe and effective treatment with the “Tixel”

Objectives: 1. The periorbital area – anatomy, histology, and aging pathogenesis.
2. Tixel mechanism of action (thermal mechanical fractional injury = TMFI) and advantages
3. Neocollagenesis and drug delivery - Comparison of EBDs.

Introduction: The periorbital region, comprising the delicate skin surrounding the eyes, is particularly prone to showing signs of aging, including fine lines, wrinkles, puffiness, and dark circles.

Many patients seek for non-invasive alternatives, that offer less downtime and minimal risk, and yet are effective. Among these, Tixel is safe and promising treatment modality for this area, offering optimal neocollagenesis and drug delivery.

Materials / method: A literature review was conducted to compare different EBDs usage in the periorbital area. This knowledge was combined with my practical experience with many energy based devices, including the Tixel.

Results: The periorbital area, surrounding the eyes, is a complex anatomical region, comprising multiple layers, including skin, subcutaneous fat, muscles, and underlying bony structures, its histology reflects its multifaceted function. The skin in this area is among the thinnest on the body, making it prone to visible signs of aging.

The Tixel can be applied safely into this region, heating the skin uniformly and open micro-channels for the delivery of essential active ingredients that synergistically improve periorbital rejuvenation potential.

Conclusion: The Tixel is optimal for periorbital area treatments, allowing individualization of the treatment and addressing all the pathologies associate with skin aging including wrinkles, texture, hyperpigmentation and skin laxity.

Declaraciones

¿Ha recibido algún tipo de financiamiento para realizar su investigación sobre esta temática?
No

¿Ha recibido algún pago, honorario u otra compensación por su trabajo acerca de esta investigación?
Si
Por favor especifique las entidades (individuo, empresa, sociedad): novoxel - industrial lecture

¿Tiene vínculos financieros con alguna entidad que podría llegar a competir estrechamente con los medicamentos, materiales o instrumentos tratados en su investigación?
No

¿Posee o ha solicitado una patente relacionada a los materiales, productos o instrumentos utilizados en su investigación?
No

Este trabajo es presentado gracias al apoyo de: novoxel - industrial lecture

KORU PHARMA - Ultimate glow up with Mesoheal® glow series: Bringing back natural radiance

CELLENIS® DERMAFILLER – A natural Approach to anti-aging

INDIBA ASIA (THAILAND) - Excellent of the first blue laser in the world for dermatology and aesthetic surgery

L'ORÉAL GROUPE - Preserving skin through the ages: New frontiers in longevity

BIOLOGIQUE RECHERCHE - Age Defying Elixir: Targeting Time's Adversaries

Objectives: - Investigate the mechanisms of cellular senescence in skin cells.
- Evaluate the impact of senescent cells on skin aging.

Introduction: Skin aging is characterized by the gradual loss of elasticity, the appearance of wrinkles, and a decline in the regenerative capacity of the skin. Cellular senescence is a major contributor to these changes. Understanding the role of senescence in skin aging is crucial for developing effective anti-aging therapies.

Materials / method: - Cell Culture: Human dermal fibroblasts cultured under standard conditions.
- Senescence Induction: Exposure to UVB radiation (30 mJ/cm²) to induce DNA damage-induced senescence.
- Senescence Markers: Analysis of SA-β-gal activity, p16INK4a expression by Western blot, and SASP factors (IL-6, IL-8) by ELISA.
- Cell lines: Human dermal fibroblasts
- Reagents: β-galactosidase staining kit, antibodies for p16INK4a, ELISA kits for IL-6 and IL-8
- Equipment: Incubator, centrifuge, spectrophotometer, Western blot apparatus

Results: Progerin expression -26.6%

Conclusion: Cellular senescence significantly contributes to skin aging through a dual mechanism of promoting chronic inflammation and causing structural degradation of the skin's extracellular matrix (ECM).

Although these senescent cells cease to divide, they remain metabolically active and secrete a variety of pro-inflammatory cytokines, chemokines, and proteases, a phenomenon known as the senescence-associated secretory phenotype (SASP).

Declaraciones

¿Ha recibido algún tipo de financiamiento para realizar su investigación sobre esta temática?
No

¿Ha recibido algún pago, honorario u otra compensación por su trabajo acerca de esta investigación?
Si
Por favor especifique las entidades (individuo, empresa, sociedad): Biologique recherer

¿Tiene vínculos financieros con alguna entidad que podría llegar a competir estrechamente con los medicamentos, materiales o instrumentos tratados en su investigación?
No

¿Posee o ha solicitado una patente relacionada a los materiales, productos o instrumentos utilizados en su investigación?
No

Este trabajo es presentado gracias al apoyo de: Biologique recherer

BLUECORE - Skin rejuvenation with three wavelengths by diode laser.

ENDYMED MEDICAL - 3DEEP: Clinical strategies and considerations

BIOLOGIQUE RECHERCHE - When science defies senescence

Objectives: Assess the long-term efficacy of a multi-ingredient anti-aging serum in improving the following parameters:
- Firmness
- Elasticity
- Skin barrier integrity
- Cell renewal stimulation
- Collagen synthesis improvement

Introduction: The serum with an enduring promise: to defy the visible signs of skin senescence. Every drop of this serum is a step towards an experiment that defies the limits of senescence thanks to science.
Its unique, avant-garde formula offers dual action thanks to 2 powerful vectors:
- Progescence®
- Pro-KL®

Materials / method: Inhibition of progerin formation by analog of serine proteinase inhibitor in dermal fibroblasts and keratinocytes.

Activation of klotho synthesis by chemical molecules from plant extract that activates the expression of the gene KL and the related protein Klotho in dermal fibroblasts.

Ex vivo study on human skin explants, cultured 10j, 4 applications (2mg/cm²) , immunostaining of progerin, image analysis for quantification of progerin level.

Reduction of water activity and high tolerance listed preservatives.

Results: Improved firmness +11% After 28 days / +23% After 56 days
Improved elasticity +17% After 28 days / +19% After 56 days

Conclusion: Aging is associated with inevitable accumulation of senescent calls.

Progescence and Pro-KL can slowdown cellular senescence both relicative senescence and premature or stress- induced senscence.

Cellular senescence is an irreversible state in which cells stop dividing. Excessive accumulation of senescent cells in tissue can adversely affect its regenerative ability, creating a pro-inflammatory environment conducive to the onset and progression of various age-related diseases. The skin is no exception to this observation either.

Declaraciones

¿Ha recibido algún tipo de financiamiento para realizar su investigación sobre esta temática?
No

¿Ha recibido algún pago, honorario u otra compensación por su trabajo acerca de esta investigación?
Si
Por favor especifique las entidades (individuo, empresa, sociedad): Biologique recherer

¿Tiene vínculos financieros con alguna entidad que podría llegar a competir estrechamente con los medicamentos, materiales o instrumentos tratados en su investigación?
No

¿Posee o ha solicitado una patente relacionada a los materiales, productos o instrumentos utilizados en su investigación?
No

Este trabajo es presentado gracias al apoyo de: Biologique recherer

Horas	Oradores	Título de la presentación	Resumen	Número
10:00	Dr Juliane MEYER	HUMAN MED AG - Q-graft® - The use of stromal vascular fraction (SVF) as a single cell suspension vs micro tissue clusters.		137682
10:30	Dr Chen LI	HANGZHOU SINGCLEAN MEDICAL - Exploration on the clinical application of layered anti-aging and comprehensive facial rejuvenation		137758
10:45	Dr Wichai HONGCHARU	SOFWAVE - Long lasting result by using synchronous ultrasound parallel beam technology		137695
11:00	Dr Ximena PAREDES	TOSKANIMED - Comparative study of the efficacy of two commercially available transcutaneous biorevitalizers		137687
11:15	Dr Guy ERLICH	NOVOXEL - The periorbital region - safe and effective treatment with the “Tixel”	Ver	137623
11:30	Dr Pinploy SRIAPIROM	KORU PHARMA - Ultimate glow up with Mesoheal® glow series: Bringing back natural radiance		137688
11:45	Sary KADAR	CELLENIS® DERMAFILLER – A natural Approach to anti-aging		137689
12:00		Sponsored lecture		137690
12:15	Dr Rassapoom SUMAETHEIWIT	INDIBA ASIA (THAILAND) - Excellent of the first blue laser in the world for dermatology and aesthetic surgery		137691
12:45	Dr Grace GAO	L'ORÉAL GROUPE - Preserving skin through the ages: New frontiers in longevity		137693
13:00		Lunch break		137746
14:00	Dr Sarawalai RAKCHART	BIOLOGIQUE RECHERCHE - Age Defying Elixir: Targeting Time's Adversaries	Ver	137694
14:15		Sponsored lecture		137696
14:30	Ho Woong CHOI	BLUECORE - Skin rejuvenation with three wavelengths by diode laser.		137748
14:45	Dr Shay LU	ENDYMED MEDICAL - 3DEEP: Clinical strategies and considerations		137749
15:00	Dr Sarawalai RAKCHART	BIOLOGIQUE RECHERCHE - When science defies senescence	Ver	137750
15:15		Sponsored lecture		137751
15:30	Dr Pablo NARANJO	INDIBA ASIA (THAILAND) - A new technology trend shaping the future of anti-aging		137752
15:45	Dr Shi XIONG	BIOHA LABORATORIES / 3SL - East Asian facial combination therapy under the new contour aesthetic theory		137754
16:15		Sponsored lecture		137753
16:30		Sponsored lecture		137755
16:45		Sponsored lecture		137747

IMCAS Asia 2024
Programa

079 - 084

INDUSTRY SPONSORED LECTURES - OPEN STAGE

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IMCAS Asia 2024 Programa

079 - 084

INDUSTRY SPONSORED LECTURES - OPEN STAGE

Las presentaciones

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IMCAS Asia 2024
Programa