Resumo

Objectives: This session explores a regenerative approach to buttock lifting and augmentation using PDLLA, human acellular dermal matrix (hADM), and fat transfer. Attendees will learn how PDLLA stimulates neocollagenesis and angiogenesis, how hADM supports tissue scaffolding and fat survival, and how the synergistic combination enhances volume retention, contour stability, and natural outcomes beyond conventional augmentation techniques. Introduction: Recent advances in regenerative aesthetics have shifted focus from mere volumization to biological rejuvenation. Combining PDLLA, human acellular dermal matrix (hADM), and autologous fat offers a synergistic strategy for buttock contouring. This approach enhances not only volume but also neocollagenesis, angiogenesis, and fat survival, creating long-lasting and natural lift effects that go beyond traditional augmentation techniques. Materials / method: Twenty female patients underwent combination therapy: PDLLA (diluted 1:6 with saline and lidocaine) injected into the deep subdermal and subcutaneous layers, followed by hADM placement to reinforce structural integrity, and micro-fat grafting for contour refinement. Clinical evaluations included 3D volumetry, ultrasound-based thickness analysis, and GAIS scoring up to 6 months post-procedure. Results: Significant and sustained improvements in buttock projection and contour were observed at 1, 3, and 6 months. Ultrasound imaging confirmed increased soft tissue density and stable fat volume retention. Histological analysis demonstrated enhanced neovascularization and fibroblast proliferation around PDLLA particles and hADM matrix, indicating true regenerative remodeling rather than transient filler effect. Conclusion: This study demonstrates that PDLLA, hADM, and fat transfer combination provides not only aesthetic enhancement but also biological regeneration. By stimulating neocollagenesis and improving fat viability within a stable dermal scaffold, this technique achieves durable lifting and contouring outcomes. It represents the evolution from volumetric augmentation toward regenerative body sculpting.