Абстракт

Objectives: Objective: Evaluation of the efficacy and tolerability of a combined therapy: preformed growth factors vehiculated through skin patting and iontophoresis in the treatment of androgenetic alopecia. Introduction: Introduction: Androgenetic alopecia is characterized by a progressive miniaturization of hair follicles usually occurring in a pattern distribution in genetically predisposed individuals. The main objectives of treatments are prevention or improvement of the hair miniaturization and prolongation of the anagen phase, in order to normalize the follicular cycle. Recent studies have shown that the different cellular components that compose the hair bulb undergo to an apoptosis process induced by the alteration of cellular control mechanisms, especially triggered by the caspases cascade within the Materials / method: Materials & Methods: We performed the treatment on 50 patients with androgenetic alopecia. The total number of sessions was 4 every month. Researcher clinical evaluation, global photography and trichoscopy with measurement of the Density / cm2 ratio by trichoscopy were collected at every session of therapy. All patients filed out a brief questionnaire of self-assessment. Results: Results: Results of our study were very promising, with improvement in most of patients seen with both global photography and trichoscopy. All patients defined the treatment as “painless and pleasant” and all were satisfied of the clinical result. Conclusion: Conclusions: The use of growth factors associated with skin patting and ionophoresis technique is a useful treatment for treating and preventing androgenetic alopecia, through a cold / hot thermal stress that stimulates the blood microcirculation, improving the tropism of the hair bulb.