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Objectives: In this study, for the first time, the results of seven years of practice on 521 patients with using thousands of simple PDO threads implanted is achieved an innovative and non-surgical technique for face and neck lift ( without any side effect and without any pain). Outcomes were assessed by Dr.Shohreh shams and patients based on GAIS scores. Introduction: In the modern world, people look for non-surgical, painless ways #FOR skin rejuvenation or even face and neck lift. A safe and affordable solution with minimum side effects and less recovery time required With this special and innovative method, the effects of face and neck lift and rejuvenation are obvious in every patient, which is attached in the photos of this article. The advantages of this method are listed below:Filling the naso-labial folders,Creating a cheek line and lifting the cheeks. Raising the crown of the eyebrows, Jawline Sharpness. Mandibular angle augmentation and neck lift. Materials / method: In this perspective review chart clinical study, a total of 521 patients were included in the study from Jan. 2015 to agust.2022. All patients underwent thread lifting using 23139 simple sterilized absorbable polydioxanone sutures with a needle (mono or mono-screw, made in Korea). Patients were followed up after 2 weeks, 4 weeks and six months after the procedure. In this method, the threads are used in some areas in the form of a mesh (horizontal and vertical) in two sessions with an interval of 10 to 14 days and in some areas of the face and neck in a back-and-forth manner. Results: A total of 521 patients with a mean age of 46.1±11.48 years (18-82), 25(4.79%) men and 496 #WOMAN (95.20%) were included in the study. The sites for the non-surgical face lifting were lower-face region( 40.69%), mid-face region( 21.41%), neck region( 16.47%), temporal region( 11.28%), forehead region( 5.92%) and inferior eyelids region( 4.20%).The mid-face region was the most common part for the procedure and the lower eyelids were the least common site. The level of satisfaction immediately after the procedure was 90% and increased in the next follow-up (two weeks later) to 92.9%. Conclusion: The splendid results of this innovative non-surgical technique using simple PDO threads are the results of a seven-year practice and experience of my _LIFE on 521 patients. Some of the patients revisit the clinic every 1-2 years to redo the procedure for longer lifting effects and rejuvenation of the skin. With these great results and a high rate of satisfaction with the _FREEDOM sensation in patients without a need for surgery, any pain or side effects, there is hope that this method will be used by aesthetics doctors for all of the people in the world.