Абстракт

Objectives: Present a regenerative medicine technique in genital reconstruction and urinary incontinence Introduction: Pelvic organ prolapse is a serious health problem and is accompanied in more than 50% by urinary incontinence. Currently, one of the surgical treatments is applying a synthetic polypropylene mesh which can cause various complications such as pain, vaginal erosion, urinary infections, damage to the bladder, among others. Minimally invasive and lower risk procedures are increasingly sought. The use of fibrin membranes is an option in the management of prolapse, since it is rich in growth factors, producing stronger tissue due to fibrosis, and new collagen produced by EGF , IGF-1 , TGF Materials / method: Descriptive, longitudinal study, observations from May 2020 to July 2024 in patients with pelvic organ prolapses that warranted surgical management. Routine colpoplasty is performed to apply 3-4 fibrin membranes to the anterior surface of the vagina and suture them with 3-0 vicryl. and closure of the vaginal mucosa with 2-0 vicril. A validated ICIQ-SF questionnaire was carried out before and after surgery to evaluate urinary incontinence. Results: 24 patients have surgery, all of which were accompanied by urinary incontinence in addition to their prolapse. Average age: 56.6 years 1-Frequency of urine loss in the preparatory period: 4 points Postoperative low to 0.28 2-Amount of urine lost before surgery: Score 4.67 Postoperative: 0.66 3-Degree of impact on daily life. Points 9.52 Postoperative:0.85 Satisfaction: 95% 3-year follow-up without prolapse recurrence Conclusion: The use of fibrin membranes is another way to treat prolapse with similar tissue in addition to the tensor facia lata, and abdominal epidermal tissue, The results presented are promising