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Доктор Michael BENZAQUEN

Дерматолог
Швейцария

I completed medical education at the Faculty of Medicine of Marseille, Aix-Marseille University (Marseille, France), and ranked first among 3000 students in the first year of medical school. I then completed my residency in Dermatology at Assistance Publique Hôpitaux de Marseille, before a fellowship in the department of Dermatology at Hôpital Nord de Marseille. My professional experiences abroad in Columbia University (New York City, USA) and Inselspital - University Hospital of Bern (Bern, Switzerland) improved my clinical skills and knowledge in Dermatology, as well as my success in ECFMG certification (USA). I graduated from several inter-university diplomas in Internal Medicine, Pediatric Dermatology, Dermatological Laser and Dermatological Surgery. My works have been published in international peer-reviewed journals and I am regularly invited as speaker in international congresses. I investigated in various fields, ranging from infectious and inflammatory diseases to onco-dermatology, laser and surgery. As the Vice-President of the Scientific Council of the French Laser Group and the coordinator of the "NextGen Dermatology" sessions of IMCAS congress, I encouraged young dermatologists in learning and practicing dermatological lasers. I am currently working in Switzerland as clinical chief in the department of dermatology of Inselspital-University Hospital of Bern and at Clinique La Prairie in Clarens-Montreux.

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Michael BENZAQUEN's публикаций (37)

Nivolumab-induced eosinophilic fasciitis: An unusual immune-related adverse event that needs to be recognized by practitioners.

Oct, 2023

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Annales de dermatologie et de venereologie

PPAR-γ regulates the effector function of human T helper 9 cells by promoting glycolysis.

Apr, 2023

T helper 9 (T9) cells promote allergic tissue inflammation and express the type 2 cytokines, IL-9 and IL-13, as well as the transcription factor, PPAR-γ. However, the functional role of PPAR-γ in human T9 cells remains unknown. Here, we demonstrate that PPAR-γ drives activation-induced glycolysis, which, in turn, promotes the expression of IL-9, but not IL-13, in an mTORC1-dependent manner. In vitro and ex vivo experiments show that the PPAR-γ-mTORC1-IL-9 pathway is active in T9 cells in human skin inflammation. Additionally, we find dynamic regulation of tissue glucose levels in acute allergic skin inflammation, suggesting that in situ glucose availability is linked to distinct immunological functions in vivo. Furthermore, paracrine IL-9 induces expression of the lactate transporter, MCT1, in T cells and promotes their aerobic glycolysis and proliferative capacity. Altogether, our findings uncover a hitherto unknown relationship between PPAR-γ-dependent glucose metabolism and pathogenic effector functions in human T9 cells. Подробнее

Nature communications

The growing importance of ultrasonography in cosmetic dermatology: An update after the 23rd IMCAS Annual World Congress (2022).

Nov, 2022

Ultrasound (US) has been used for many years in the field of medicine. Many specialties have embraced US as a quick, painless, and relatively inexpensive tool to assist the clinician in determining anatomy, pathology, and aid in diagnostic or therapeutic procedures. US allows for precise mapping of cutaneous and subcutaneous structures in the face, in particular vascular structures. The use of US leads to reduced chances of complications and clinical failures, rendering more safety and high quality. Подробнее

Journal of cosmetic dermatology
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научные общества Michael BENZAQUEN (5)