摘要

Objectives: We sought to evaluate the efficacy, tolerance and safety of Heterologous Type I Collagen for the treatment of steroid-induced dyspigmentation and cutaneous atrophy due to intralesional triamcinolone treatment of a lateral epicondylitis. Introduction: Steroid-induced atrophy is a well-known complication of intralesional steroid use and, although typically self-limited, can be distressing to patients. This case report describes the successful treatment of cutaneous atrophy and dyspigmentation on the elbow joint secondary to intralesional steroid injections for lateral epicondylitis using Heterologous Type I Collagen (HTIC). Materials / method: A 26-year-old woman with Fitzpatrick skin type IV presented with a steroid-induced cutaneous atrophy and dyspigmentation was treated with Heterologous Type I Collagen (HTIC) intradermal injections. 100mg of HTIC sterile powder, dissolved in 5ml of normal saline was injected to the affected area. The patient received 4 treatments, once every two weeks. Results: The area treated with HTIC demonstrated skin quality improvement after the first session and complete resolution of the lesion after the fourth session. The patient reported minimal to moderate pain and there were no side-effects. Conclusion: HTIC is a potential new treatment option for steroid- induced cutaneous atrophy and dyspigmentation. The treatment is highly efficient and safe for use. Further assessment with more extensive clinical trials are necessary.