Objectives: The purpose of this presentation is to provide evidence-based medicine on their uses in aesthetic medicine. Introduction: The use of exosomes has increased significantly over the past several years in aesthetic medicine. There is a myriad of potential uses for these extracellular vesicles that promote intracellular communication. Materials / method: Literature review looking at the current publications in the exosome space was used. Results: At present, the current literature landscape for the use of exosomes in medical dermatology and aesthetics is small. The published data supports that wound healing is enhanced with the use of exosomes and that within aesthetics, procedures can heal faster than traditional therapy as well as accelerating hair growth in many individuals. Conclusion: Exosomes have incredible potentials in dermatology and in aesthetic medicine. We must demand that appropriate clinical trials are performed to verify the current hype surrounding these products and determine how best to use them to benefit our patients.