摘要

Objectives: 1. The function and pathway for bioregeneration and biostimulation of Nucleotides 2. The differences between Polynucleotides vs Nucleotides and their similarities 3. Medical and aesthetic applications of using PN for multiple eg Pigmentary disorders, atrophic scarring, aging skin and skin injury. 4. Method of applications 5. Combination therapy that can be included with PN in current practices Introduction: Medical application of PDRN, PN(POLYNUCLEOTIDE) for multiple skin aging and related dermatological problems in asian skin such as pigmentary disorders, acne scars, photoaging are a constant issues among them. Creating a alternative solutions that works and can be corrected with just the focus on epidermal and dermal repair, remodelling with nucleotides are one of the future of regenerative aesthetics. My presentation will cover corrective issues for skin mainly Pigmentary disorders, atrophic scarring and aging skin with use of nucleotides. Materials / method: 1.GAIS Scoring 2.Modified MASI scoring 3. Retrospective Study with 3D photography Results: Positive results and visible improvements over a observational period of 6 months Conclusion: Polynucleotide and Nucleotide have good property of bio stimulation for repair, bio regeneration and bio stimulation for for the epidermal and dermal tissue of the skin.