摘要

Objectives: Discuss the effect of regenerative medicine PRP/PRF in different Gynecological indications and conditions that affect the female reproductive system, including stress urinary incontinence, vaginal atrophy, and sexual dysfunction, as a stand alone or add on to the traditional treatment options for these conditions. Introduction: Platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) are autologous blood-derived products that have gained significant attention in various medical fields due to their regenerative and healing properties. While primarily used in orthopedics and dermatology, PRP and PRF have recently emerged as promising therapies in the field of gynecology. Materials / method: PRP and PRF have shown promise in several areas. In the management of post surgical or post laser PRP have been investigated to enhance the efficacy of surgical repairs and promote tissue healing. For stress urinary incontinence, PRP has been explored as an adjunct therapy to augment surgical procedures or as a standalone treatment, aiming to strengthen the urethral and pelvic floor muscles. Additionally, PRP and PRF have been considered as potential options for addressing vaginal atrophy and sexual dysfunction by promoting vaginal tissue rejuvenation and improving local blood supply. Results: Preliminary studies and anecdotal evidence suggest that PRP and PRF therapies in gynecology are generally safe and well-tolerated, with minimal adverse effects reported. However, more rigorous clinical trials and long-term follow-ups are needed to establish their efficacy, optimal dosing protocols, and standardized treatment regimens. Conclusion: The application of PRP and PRF in gynecological indications holds promise as a non-invasive or adjunctive treatment option. These autologous blood-derived therapies have the potential to promote tissue regeneration, enhance healing, and improve symptoms in various gynecological conditions. Continued research and clinical trials will help further elucidate their effectiveness, ensuring evidence-based integration into gynecological practice.