摘要

Objectives: To evaluate the capabilities of using ultrasound elastography and B-histology in studying skin quality before and after injection of HA-based gel. Introduction: Ultrasound examination makes it possible to assess the condition of the dermis and the subcutaneous fat tissue (SFT) before and after corrections. At the same time, the method has disadvantages, which everyone is well aware of: ultrasound diagnostics is an operator-dependent method. We can’t characterize tissues in numbers and statistically process the data, compare them in dynamics. Elastographic methods of ultrasound wide our opportunities, allow defining tissues strain in numbers more precisely, assessment of therapy dynamics and the effect on soft tissues. Materials / method: The study involved 32 patients (average age of 46 years). Condition of the dermis and the SFT was assessed using the same technical characteristics of the ultrasound machine (Gain 45, DR 135) and Ultra high-frequency probe (12.5 – 23 MHz) at four identical points before and after the therapy. Ultrasound diagnostics compared tissue sonograms in B-mode, B-histology (measurement and calculation of the gray gradation distribution of ultrasound echo signals within a closed area), as well as assessed the "hardness" of tissues over time using strain elastography and shear wave elastography. Results: The elastography data obtained: SWE and SE, B-hystology enable to use these methods for quantity evaluation of face soft tissues (dermis and subcutaneous tissue) conditions and may be used as an excellent tool for researches and routine practice. Subdermal skin-booster injections have a positive influence on the dermis quality, significantly increasing its density and amount of white pixels according to multiparametric ultrasound examination. Conclusion: The resulting data of the study makes it possible to recommend the widespread use of a multiparametric approach in ultrasound assessment of facial soft tissues in cosmetology.