摘要

Objectives: The objectives is to illustrate clinical experience with a new product and highlight the use of PrabotulinumtoxinA injections as an alternative therapeutic option for Raynaud's, focusing on its ability to improve microvascular circulation and alleviate associated symptoms. Introduction: Raynaud's phenomenon is a vascular disorder characterised by episodic vasoconstriction in response to cold or emotional stress, primarily affecting the extremities, such as the fingers and toes. While oral treatments are commonly used to manage Raynaud's, some patients do not respond adequately or are averse to these treatments due to systemic side effects. Materials / method: The standard injection technique was employed, with 5 units of PrabotulinumtoxinA administered into each side of the base of every digit of a 75-year-old male patient with Raynaud's affecting both hands. The dilution ratio used was 0.5 ml per 50 units vial. 100 units injected in total. Results: Following the PrabotulinumtoxinA injection protocol, the patient reported a significant improvement in hand circulation. Notably, the patient experienced a complete cessation of fingertip cracking, which had been a persistent and distressing symptom. Conclusion: The successful outcome observed in this case study suggests that PrabotulinumtoxinA injections may offer a promising therapeutic option for Raynaud's phenomenon, particularly in cases where traditional oral treatments have proven ineffective or are not preferred due to systemic side effects. The improvement in microvascular circulation and the resolution of fingertip cracking contributes to the growing body of evidence supporting the use of PrabotulinumtoxinA as a therapeutic approach for Raynaud's phenomenon.