摘要

Objectives: This network meta-analysis aimed to compare different conventional dressing options based on re-epithelialization time and side effects for split-thickness skin graft donor sites. Introduction: Over 160,000 skin grafts are conducted annually in approximately one out of every three burn hospitalizations, since they are primarily simple and quick. This network meta-analysis aimed to compare different conventional dressing options based on re-epithelialization time and side effects for split-thickness skin graft donor sites. Materials / method: A thorough systematic review and network meta-analysis was conducted in accordance with PRISMA guidelines. A comprehensive search was performed through Medline, Cochrane, and Embase databases, up to the year 2023 without time limitation. Results: This study performed a network meta-analysis of 25 unique randomized controlled trials published between 1983 up to 2022. We found that Alginate is the most frequently used, followed by Paraffin gauze. Nonetheless, Povidone-Iodine was the most effective (90.4%), followed by hydrocolloid (87.9%). Petrolatum (73.5%) is associated with faster re-epithelization than alginate (40.6%) and paraffin (18.1%). Cotton gauze ranked as the worst modality for skin-graft donor-site dressing (3.9%). Conclusion: This study serves as a guide for the selection of proper dressing for patients undergoing partial-thickness skin-graft harvest. Even though povidone-iodine was the most effective, we recommend further research comparing other factors for selecting dressings, such as wound and patient characteristics, availability, and costs of dressings.