摘要

Objectives: We watnt to show the effectiveness of electroporation added to microabrasion, increasing the transdermal delivery of active ingredients such as Lumicen gel and TKN HA xs 2% solution, TKN HA mw 2%, in the treatment of the patient. Introduction: Hyperkeratosis is first of all an adaptive physiological phenomenon that aims, through the accelerated production of strongly keratinized cells, to strengthen the resistance of the epidermis. Hyperkeratosis is the thickening of the stratum corneum (the outermost layer of the epidermis), often associated with the presence of an abnormal amount of keratin and also usually accompanied by an increase in the granular layer. It can be caused by vitamin A deficiency or chronic exposure to arsenic. From the analysis of the studies, two types of approaches for the treatment of hyperkeratosis. Materials / method: Technology: MesojectGun Machine parameters: Electroporation 5 Contact degree 5 Product dosage 3 Frequency 5 Assets: Lumicen solution 1ml + Lumicen gel 1 ml - 2ml of the mixture We make this mixture because the substances having different molecular weight ensure penetration into different layers of the skin. +TKN HA MW2% - 1ml + TKN HA XS2% - 1ml - 2ml We make this mixture because substances with different molecular weights act in different ways. The low molecular weight one acts faster and for less time; the one with medium molecular weight, on the other hand, ensures later and longer hydrati Results: The patient adhered well to the clinical treatment, as it proved to be effective and painless. The clinical improvement of the patient shows that the choice of ELECTROPORATION + MICROABRASATION, to facilitate the transdermal delivery of the chosen assets was satisfactory. And the choice of active ingredients was effective for hydration and skin reorganization of the patient’s plantar regions D and E. Conclusion: PDRN has the capacity for skin hydration, high cell regeneration power and is a powerful anti-inflammatory. TKN HA XS 2% and TKN HA MW 2% have high moisturizing power and increased skin elasticity. With the blends carried out we achieve distinct depths (lumicen gel and solution) and prolonged action (TKN HH XS 2% and TKN HA MW 2%). The patient is in monthly follow-up for reassessment of the conduct and repetition of the indicated procedure whenever necessary. This treatment can be effective at any time of the year and is indicated for all patients.