摘要

Objectives: Review current EBD Use for the treatment of acne with a focus on real world data on the Use of a contact-cooled 1726 nm Laser System in the Treatment of Acne Vulgaris and Other Associated Conditions Introduction: Acne vulgaris is one of the most prevalent skin disorders, affecting individuals of various ages and skin types. Although traditional treatments can be effective, they may also lead to considerable adverse effects, and their results might not be long-lasting. A 1726 nm laser, coupled with a contact cooling system became FDA cleared in 2022 and has shown promising data at 1-year post-treatment. Materials / method: 125 consecutive patients with acne were treated, after FDA clearance, with a contact cooled 1726nm laser. They were evaluated 24 months after 3 monthly treatments for degree of IGA improvement, inflammatory lesion count reduction and comedonal count decreases. Adverse events were also evaluated. 24 month “real-life” data was then compared to the 12-month data seen in the original pivotal FDA trial. . Results: Much like in the original FDA trial, efficacy assessment showed a continuous improvement of the patient’s acne during the 24-month follow-up period. Compared to baseline, there was a notable reduction in evaluated parameters that were similar to those seen in the FDA trial. Complications were rare and only 2 patients sought retreatment at 18 months. Conclusion: This study shows for the first time that real life experience with a contact-cooled 1726 nm laser system results in the long-lasting resolution of severe acne The observed data was similar to that seen in the pivotal FDA trial. Discussion will also include why complications can occur and the mechanism of response seen with other sebaceous gland disorders.