The role of Pegylated Hyaluronic acid fillers (PEG-HA) in the improvement of cancer patients survivors (CPS) fascial cosmetic appearance
Objectives: To study the safety and the effect of cosmetic non surgical fascial treatment in cancer survivors using Pegylated Hyaluronic acid fillers and the effect of improving facial appearance in reflection on patient quality of life.
Introduction: Cancer treatments often negatively result in changes to fascial natural volume and appearance. Fascial aesthetics in cancer patients is an emerging area of study that focuses on the relationship between restoring the physical appearances and QOL. Incorporating fascial aesthetics into cancer care aligns with the principles of holistic health, recognizing the interconnectedness of physical, emotional, and psychological well-being. This case series study to present the safety and the cosmetic outcomes of a cohort of CPS who has been treated with PEG-HA dermal fillers.
Materials / method: The study has collected retrospectively qualitative surveys and self-assessment of 100 CPS treated with PEG-HA to improve the fascial appearance following completion of anti-cancer treatment, over the period of 24 months from June 2023 to June 2024. Collecting subjective data from individuals regarding their perceptions of their facial aesthetics using Likert Scale Questions (LSQ) on a scale from 1 to 5 of improvement in the fascial appearance and yes or no response on the overall well-being and QOL. Data was collected by one-to-one telephonic interview; all ethical considerations has been ap
Results: Out of the 100 CPS studied a chi-square test was conducted to examine the relationship between satisfaction with fascial appearance and CPS wellbeing and QOL. The result indicated a significant association between satisfaction levels of fascial appearances and the likelihood of improvement of the wellbeing and QOL, of 80% p < 0.05 of patients reported satisfied or very satisfied and no report of dissatisfied. To date, the use of PEG-HA has not been associated with increase adverse events in CPS.
Conclusion: This study identified PEG-HA dermal fillers has shown to be a safe and practical treatment with a visual and qualitative way of examining the relationship between satisfaction with fascial cosmetic appearance and improvement of wellbeing and QOL. By combining this with statistical testing, such as the chi-square test, we have determined the observed patterns are statistically significant and not occurred by chance in this group of patients. We recommend further research in the field of aesthetics in oncology.