David J GOLDBERG Prof
皮肤科医师
Prolactin Receptor Inhibition and Hair Growth: The New Frontier
Objectives: Androgenic Alopecia is a common cosmetic concern for both men and women. An increasing number of women are seeing this at a younger age. Uses of GLP1 agonists appear to have accelerated the loss of scalp hair in many and at a younger age. There has not been a significant novel treatment for this condition in decades
Introduction: Prolactin receptors are seen on all hair follicles. Exposure to prolactin leads growing anagen hair follicles to become catagen and telogen hair follicles – with resultant hair loss. Blocking the prolactin hair receptors leads to conversion of telogen hairs back to thicker pigmented anagen hairs
Materials / method: Prolactin receptors are seen on all hair follicles. Exposure to prolactin leads growing anagen hair follicles to become catagen and telogen hair follicles – with resultant hair loss. Blocking the prolactin hair receptors leads to conversion of telogen hairs back to thicker pigmented anagen hairs. This presentation will review new data on the efficacy and safety of the prolactin hair receptor blockage in androgenic alopecia in rodents, monkeys and humans. Both safety and efficacy will be discussed
Results: Prolactin Receptor Inhibition and Hair Growth represents a totally novel approach to treating unwanted hair loss
Conclusion: Prolactin Receptor Inhibition and Hair Growth represents a new frontier in the treatment of androgenic alopecia. This approach offers a promising alternative to other less successful treatments.