摘要
Xanya SOFRA WEISS 医师
神经科医师
Menopause, hormonal imbalance & dysbiosis, why women suffer and why they don’t have to
Objectives: The menopausal transition precipitates bothersome vasomotor symptoms, mood disruption, temporary cognitive dysfunction, weight gain that persists or rebounds despite lipolysis or regular gym visits, genitourinary symptoms, and other disease processes that reduce the quality of life of affected women. This presentation investigates and reports the best technique combinations with the least side effects to alleviate menopausal symptoms and improve both physique, wellness status, and quality of life
Introduction: Menopause is characterized by altered responsiveness to gonadal steroid feedback, wide hormonal fluctuations, dysbiosis, increased stress levels due to cortisol imbalance, persistent weight increase, including visceral fat increase, higher incidence of fatty liver, all of which are resistant to diet and exercise, Menopausal women may exhibit increased hunger due to leptin-ghrelin disharmony, inflammation which speeds up the aging process, anxiety and depression, since serotonin, the protagonist of depressive and anxiety disorders is mainly produced in the gut
Materials / method: A total of 758 publications were reviewed for this presentation. A number of hormonal optimization, and gut balancing methods were combined, including innovative diets, nutraceuticals that balance reproductive hormones, probiotics, methods that boost metabolism and optimize the ghrelin/leptin balance while controlling cortisol to control hunger, and various exercise methods, including innovative exercise techniques. Hormone therapy (HT) treatment can be effective for perimenopausal symptoms but its use has been stymied by concerns about health risks observed in postmenopausal older women.
Results: No lipolysis method can work with people who are stress eating and are metabolically imbalanced exhibiting depressive and anxiety symptomatology. Overeating, obesity, and inflammation are the starting points of a process that evolves into hormonal and appetite dysregulations, complemented by excess lipids, and lipoproteins that result in the emergence of diabetes, CVD and respiratory disease. Depression due to hypothyroidism reinforces food cravings and snacking as a coping mechanism. Metabolic dysfunction has been associated with mood disorders.
Conclusion: Aesthetic body shaping is not enough to offer quality of life. Current popular procedures can offer a limited improvement but without hormonal optimization results rebound and in the mind of the consumer they cost more than what they are worth. Focus should shift from the external beauty to internal balance that involves combating dysbiosis and establishing hormonal optimization
披露 - Xanya SOFRA WEISS
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Published on 2026年 7月 30日 - Recorded during IMCAS Asia 2026