摘要

Objectives: This session aims to define how biorevitalizer priming—through hyaluronic acid–based hydration, amino-acid–mediated dermal modulation, and improved extracellular matrix responsiveness—amplifies the tightening effects of monopolar RF. It further aims to present objective evidence demonstrating superior gains in elasticity, hydration, redness reduction, and lower-face contouring, alongside higher GAIS and 3D imaging improvements compared with RF alone. The goal is to define a safe, reproducible combination protocol that delivers more consistent, natural, and long-lasting clinical outcomes. Introduction: Monopolar RF, which is commonly applied as a noninvasive aesthetic treatment option for skin laxity through stimulation of dermal collagen remodeling. Although results may depend on individual skin quality. Skin pre-treatment, prior to RF exposure with a biorevitalizer formulation of hyaluronic acid and amino acids might serve yet another indication for an improved hydration state as well as dermal responsiveness, which would improve the efficacy of RF. Materials / method: This study compared monopolar radiofrequency (6.78 MHz, 5 cm² tip, 600 total shots) alone vs. monopolar radiofrequency (RF) preceded by injectable biorevitalizer priming. Results showed that combining biorevitalizer (1% HA + amino acids) with RF significantly improved skin elasticity, hydration, and facial contouring, with better GAIS and 3D imaging outcomes. Results: The combination group demonstrated superior improvements in: - Skin elasticity - Hydration and redness scores - Volume contour and skin laxity, particularly in the lower face and jowl region Patient satisfaction was higher in the combination group, with no significant difference in adverse effects or pain scores between groups. Conclusion: Biorevitalizer priming prior to monopolar RF treatment significantly enhances clinical outcomes in skin tightening and rejuvenation. This combination represents a safe, effective, and customizable protocol for practitioners seeking improved, longer-lasting results in non-invasive facial treatments.