摘要
Athanasios PAVLIDIS 医师
皮肤科医师
Baricitinib combined with platelet-rich plasma in alopecia areata: real-world clinical experience and case-based outcomes
目标: We're sharing our hands-on experience with using a combination of Baricitinib and PRP therapy to treat patients with alopecia areata that hasn't responded to other treatments. The patients we worked with were adults who had multiple areas of hair loss, complete hair loss, or recurring hair loss, and had already tried other treatments like corticosteroids and minoxidil without success. We gave them Baricitinib in doses of 2-4 mg per day, depending on how severe their condition was and what other health issues they had. At the same time, they received PRP treatments.
介绍: Alopecia areata is a long-term condition where your body's immune system attacks your hair follicles, leading to hair loss that can be really tough to deal with. Recently, some new medicines called Janus kinase inhibitors, like Baricitinib, have become available and they're changing the way we treat this condition, especially for people with moderate to severe hair loss. Another treatment that's been getting attention is platelet-rich plasma, or PRP, which uses the growth factors in your blood to help stimulate hair growth.
材料 / 方法: Clinical evaluation demonstrated progressive hair regrowth beginning approximately 8–12 weeks after treatment initiation, with more pronounced improvement observed after the third PRP session.
结果: Combination therapy appeared particularly beneficial in patients with extensive scalp involvement and long disease duration, providing accelerated regrowth and improved hair density compared with prior monotherapies reported by the patients themselves. Eyebrow and beard involvement also showed partial-to-marked recovery in selected cases. Treatment was generally well tolerated, with no serious adverse events observed during follow-up. Mild transient headache and scalp discomfort after PRP were the most common complaints.
总结: Our findings indicate that using Baricitinib along with PRP could be a really effective way to treat alopecia areata, especially in tough cases. This combination might help hair
披露 - Athanasios PAVLIDIS
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