Objectives: Each scar type has a different structural cause warranting a customized approach. Introduction: Many cosmetic options exist to address these changes individually, but little literature exists about the safety and efficacy of combining such procedures and devices as hyaluronic acid, corticoids, laser and why not botulinum toxin. Materials / method: A Medline search was performed on combination treatments because it relates, and results are summarized. In a personal practical application for using toxin is discussed_ Results: Review of the literature revealed multiple single options for scar treatment with minimal evidence in the literature found on the safety and efficacy of toxins. Conclusion: The authors' experience is that combining treatment techniques if necessary can be performed safely and synergistically with optimal patient outcomes.