Hossein MOSAFERIAN 医师

美容整型外科医师, 伊朗

Nanofat Transfer for Acne Scar

再生医学
针剂注射

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Acne scars are usually the result of inflamed blemishes caused by skin pores engorged with excess oil, dead skin cells and bacteria. The pore swells, causing a break in the follicle wall. Shallow lesions are usually minor and heal quickly. But if there is a deep break in the wall of the pore, infected material can spill out into surrounding tissue, creating deeper lesions. The skin attempts to repair these lesions by forming new collagen fibers. These repairs usually aren’t as smooth and flawless as the original skin.

There are four types of acne scars:

1. Rolling scars: Broad depressions with sloping edge.
2. Boxcar scars: Broad depressions with sharply defined edges.
3. Atrophic scars: Flat, thin scars or depressed scars.
4. “Ice-pick” scars: Usually small, yet obvious holes in the skin.


Nanofat grafting for acne scar

Nanofat grafting refers to the very small particles of fat that are specifically filtered and emulsified and used for areas to be injected, in this process the harvested fat filtered and emulsified to obtain nano-particles.

This emulsion contains high percentage of stem cells, endothelial cells, monocytes, macrophages and granulocytes which activation of stem cells increases collagen production. During processing and filtering of harvested materials, many fat cells die (cell apoptosis).

Nanofat grafting has been shown to have beneficial effects in the treatment of scars, hyperpigmentation, and dark spots. However atrophic and rolling scars as well as hyperpigmentation had greatest improvement with this treatment. In our practice sharp needle intradermal fat grafting (SNIF) had greatest response for the treatment of atrophic and rolling scars and topical application of nanofat after skin resurfacing techniques would improve dark spots as well as post inflammatory hyperpigmentation (PIH).

Treatment of PIH with best topical and systemic approaches last for several weeks and may even last for more than 5 years if left untreated. This type of pigment is different than normal dark spots because it is a result of inflammation. PIH with other causes such as complication of energy-based devices would aggravate with further treatments and manipulations, however nanofat application in combination with traditional treatments had rapid and significant improvement in such cases.

The most important step of all is to protect treatment areas from the sun. UV rays are the enemy of acne scars, dark spots and pigmented areas. They trigger inflammation and spike melanin production, causing dark spots and PIH to become even darker and harder to fade.

To minimize swelling in the face one may use cool, clean compresses or ice wrapped in a dry cloth. Mild cooling of the area will help reduce inflammation and rapid recovery, however too much ice may limit blood circulation to the area and conversely increase inflammation and pigmentation.

Tagged: 再生医学, 针剂注射

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Hossein MOSAFERIAN 医师

美容整型外科医师, 伊朗

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