Abstract

Objectives: To evaluate the safety, feasibility, and clinical outcomes of fractional thermal–mechanical resurfacing for treating dyschromia, roughness, and rhytides in the areola and labia majora. Attendees will learn about treatment protocols, patient-reported outcomes, and how AI-assisted image analysis compares with physician-based assessments in aesthetic evaluation of sensitive anatomical regions. Introduction: While fractional thermal–mechanical resurfacing is established for facial rejuvenation, its application to sensitive areas like the areola and labia majora remains largely unexplored. This study investigates the safety and efficacy of such technology in addressing dyschromia, textural irregularities, and rhytides in these regions. Materials / method: Eight patients with areolar or labial aesthetic concerns received three sessions of fractional thermal–mechanical resurfacing at monthly intervals. Standardized photographs were taken at baseline, after each treatment, and at a six-month follow-up. Blinded investigators assessed improvements in pigmentation, texture, and wrinkles using a quartile scale. Patient satisfaction was measured through structured surveys. AI-assisted image analysis was used to quantify pigmentation, roughness, and fine lines, and compared with physician-based evaluations. Results: Clinical evaluation revealed noticeable improvements in pigmentation, skin texture, and wrinkle reduction in the treated areas following the three treatment sessions. At the six-month follow-up, the aesthetic enhancements were maintained relative to the pre-treatment baseline, demonstrating a sustained benefit. No significant adverse events were observed. Conclusion: Fractional thermal–mechanical resurfacing demonstrates promise as a safe and effective modality for aesthetic enhancement of the areola and labia majora. The observed improvements in skin tone and texture, coupled with sustained results at six months, suggest that this modality can be a valuable tool for addressing aesthetic concerns in these less commonly treated areas. Further controlled studies with larger cohorts are warranted.