Objectives: To update the use of phototherapy "at the age of biologics" for vitiligo
Introduction: Phototherapy was introduced in the treatment of vitiligo patients more than 100 years ago.
Forty years ago the development of narrow-band UVB (NB-UVB) fluorescent tubes was a major step forward.
The clinical availability of new drug treatments open the possibility of very effective treatment combinations
Materials / method: We have reviewed the clinical results on the treatment of vitiligo of:
NB-UVB alone
NB-UVB combined with topical calcineurin inhibitors
NB-UVB combined with topical JAK inhibitors
NB-UVB combined with oral JAK inhibitors
NB-UVB combined with subcutaneous implants of afamelanotide
NB-UVB combined with oral and topical anti oxidants
Results: The combination with NB-UVB improves the treatment outcome of topical calcineurin inhibitors, topical JAK inhibitors, oral JAK inhibitors, subcutaneous implants of afamelanotide and oral and topical anti oxidants
Conclusion: NB-UVB remains a cheap, effective and safe treatment for vitiligo and its combination with new drug treatments can be still more positive with an enhancement of efficacy and a substantial decrease of costs
Disclosures
Did you receive any funding to support your research for this TOPIC?
No
Were you provided with any honoraria, payment or other compensation for your work on this study?
No
Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No
Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No
This work was not supported by any direct or non direct funding. It is under the author's own responsability