Objectives: New physical treatments (laser, radiofrequency, intense pulsed light [IPL]), enable
good ambulatory long-term management for all HS stages.
We performed a literature research to evaluate all laser, light and EBD sources that have been used to treat hidradenitis and performed a trial, analyzing the efficacy of local treatment with a combination of intense pulsed light (IPL) and radiofrequency (RF).
Introduction: Hidradenitis suppurativa (HS) is a chronic, inflammatoryskin disease with high burden for patients and limited treatment options characterized by abscess formation and mutilating scar formation in the body folds. HS patients are treated both conservatively
and surgically mostly by dermatologists, which requires extensive knowledge of the
pathogenesis, trigger factors, comorbidities and treatment options.
New physical treatments (laser, radiofrequency, intense pulsed light [IPL]), enable
good ambulatory long-term management for all HS stages.
Materials / method: We performed a literature research to evaluate all laser, light and EBD sources that have been used to treat hidradenitis and performed a trial, analyzing the efficacy of local treatment with a combination of intense pulsed light (IPL) and radiofrequency (RF).
The retrospective study included 111 patients who were treated with IPL+RF at least 5 times. Primary endpoint was the change in surgical interventions. Secondary endpoints included additional patient-reported outcomes, e.g., effects on their qualityof life.
Results: The most frequent technology used to treat acne inversa was reported to be Nd Yag lasers for hair removal and some anti inflammatory result. Some other wavelengths were used with the same purpose and similar result of reducing the sxmptoms by 30-60 %.
Pulsed dye lasers and PDT were less succesful. Surgical ablative lasers have been rreoprted as an alternative to classic surgers but secoindary healing and less bleeding.
In the trail of IPL+RF the number of surgical interventions decreased from 3.2 to 0.3 per year (p < 0.001). Secondary endpoints were also significantly improved: The days of s
Conclusion: This retrospective assessment of patient-reported treatment outcomes of 50 HS cases after treatment with LAight revealed a significant reduction of required surgical interventions and sick-days along with improved quality of life. Thus, it appears that IPL+ RF treatment not only improves disease activity, but also secondary care aspects. Future studies will need to confirm these findings in a controlled setting.
Declaraciones
¿Ha recibido algún tipo de financiamiento para realizar su investigación sobre esta temática?
No
¿Ha recibido algún pago, honorario u otra compensación por su trabajo acerca de esta investigación?
No
¿Tiene vínculos financieros con alguna entidad que podría llegar a competir estrechamente con los medicamentos, materiales o instrumentos tratados en su investigación?
No
¿Posee o ha solicitado una patente relacionada a los materiales, productos o instrumentos utilizados en su investigación?
No
Este trabajo no cuenta con el apoyo de ningún financiamiento directo o indirecto. El autor asume plena responsabilidad sobre el mismo.