Objectives: We present a case of 30 years old women who suffered from
connective tissue disorder diagnosed as Scleroderma by her
dermatologist. She had facial atrophy, more pronounced on right
side, “salt and pepper” skin appearance with hyperpigmentation. She
complained about difficulties with mouth opening and she also had
asymmetrically positioned earlobes and eyeballs. Her skin presented
decreased elasticity.
Introduction: Introduction: Scleroderma is a type of autoimmune disease that
affects connective tissue. It is more common in women, appears
between ages of 30 and 50, but affects all races. It is characterised by
increased synthesis of collagen, damage to small blood vessels,
activation of T lymphocytes and production of altered connective
tissue. Scleroderma can be classified as localised and systemic.
Treatment is symptomatic. The latest advancement in the treatment
is the application of the adipose tissue and regenerative cells that are
located within it. Subcutaneous adipose tissue is a source of
hetero
Materials / method: Microfat was injected in subcutaneous layer in withdrawal fashion in the following regions: zygomatic, nasolabial fold, jaw line, buccal and perioral region. During the first procedure we performed lipofilling with 58 ml, 3 months after and we injected 30 ml of microfat and 5 months after the second surgery, we injected 30 ml of microfat on the right side of the face and also 15 ml of previously prepared nanofat that we applied using nappage technique.
We followed up the patient between the procedures and during one year after the last surgery. For the evaluation of the result we used pictures
Results: Results: All procedures were uneventful and well tolerated by the
patient. Both, the patient and surgical team were pleased with the
final aesthetic outcome. The skin appearance and the symptoms
such as mouth opening were significantly improved as well. We present pictures before and after each procedure.
Conclusion: Conclusion: This procedure is very useful for mitigating symptoms of
tissue fibrosis, improving the quality of skin and quality of patients
life. More cases are needed before this procedure becomes standard
for connective tissue disorders treatment.
Declaraciones
¿Ha recibido algún tipo de financiamiento para realizar su investigación sobre esta temática?
No
¿Ha recibido algún pago, honorario u otra compensación por su trabajo acerca de esta investigación?
No
¿Tiene vínculos financieros con alguna entidad que podría llegar a competir estrechamente con los medicamentos, materiales o instrumentos tratados en su investigación?
No
¿Posee o ha solicitado una patente relacionada a los materiales, productos o instrumentos utilizados en su investigación?
No
Este trabajo no cuenta con el apoyo de ningún financiamiento directo o indirecto. El autor asume plena responsabilidad sobre el mismo.