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Objectives: This study evaluates the efficacy and safety of PLLA injections in patients with moderate to severe atrophic acne scars. Introduction: Poly-L-lactic acid (PLLA) is a biostimulatory injectable widely used for facial volumization and collagen induction. Its application in treating atrophic acne scars has gained attention due to its long-term neocollagenesis effects. Materials / method: Thirty-eight patients (24 females, 14 males; age range 22–45 years) with atrophic acne scars were treated with injectable PLLA over a 3-month period. Each patient received 2–3 treatment sessions at 4–6 week intervals. Standardized photographs and acne scar grading using the Goodman and Baron scale were recorded at baseline and 3 months after the final session. Patient satisfaction and adverse effects were also evaluated. Results: At 3-month follow-up, 79% of patients showed at least a one-grade improvement in the Goodman and Baron scale, while 34% achieved a two-grade improvement. Patient satisfaction was high, with 82% reporting “good” to “excellent” results. No cases of nodule formation or vascular complications were observed. Mild transient edema and bruising occurred in 18% of cases. Conclusion: PLLA injection is a safe and effective modality for the treatment of atrophic acne scars, offering sustained clinical improvement with minimal adverse events. Its biostimulatory properties make it a valuable option for patients seeking long-term scar remodeling