Objectives: Adjustable Fat Repositioning with Intraoral Anchoring (AFRIA) in Transconjunctival Lower Blepharoplasty via a short incision

Objectives: Objective

This lecture aims to provide a comprehensive understanding of the clinical outcomes of fat grafting for eyebrow enhancement through a detailed analysis of retrospective case studies. Attendees will learn about the efficacy, safety, and best practices associated with this technique, with a focus on achieving optimal aesthetic results.

Learning Outcomes

Understanding the Procedure and Its Applications

Participants will gain a thorough understanding of the fat grafting procedure and its specific application for eyebrow enhancement.
Discussion will include the fundamentals of fat har

Objectives: This research focuses on a biologically active, regenerative alternative for sustained periorbital rejuvenation.
1. Evaluate the Efficacy of ACF Filler
2. Comparison with other autologous-derived materials (such as Coleman fat, nanofat, and ACF).
3. Analyze Patient Satisfaction and Clinical Outcomes
4. Investigate the Regenerative and Biostimulatory Potential of ACF
5. Ensure Safety and Minimize Complications
6. Validate ACF as a Long-Lasting Alternative to Traditional Fillers
7. What to bring from Autologous-Derived Materials to the Future of Regenerative Biomaterials

Introduction: Infraorbital dark circles are a prevalent aesthetic concern worldwide​. This condition arises from anatomical and physiological factors​. The periorbital skin is among the thinnest in the body and, with age-related collagen loss, becomes increasingly translucent—revealing the underlying vascular​. Concurrently, atrophy of periorbital fat pads and surrounding support structures leads to depression and shadowing​. By correcting root structural causes rather than merely masking symptoms, these approaches offer the potential for more resolution of infraorbital dark circles​.

Materials / method: For Animal Study:
Characterization Methods: Histology, Immunostaining, Western blotting, cell viability assays.
Proteomic Analysis: Evaluation of bioactive components in ACF.
Evaluations：Collagen synthesis/degradation, Skin barrier function, Skin filling effectiveness, Collagen remodeling process, dermal thickness, fibroblast expression, antioxidase expression
For Clinical Study: Subjects with dark circles.
Intervention: Single session of Intradermal ACF injection with 8 months follow-up.
Outcome measures: Clinical improvement assessed via Global Aesthetic Improvement Scale (GAIS)

Results: 1. Patient satisfaction:
86% reported being "highly satisfied" or "satisfied." Improvements included brighter, tighter, and smoother infraorbital skin.
2. Clinical outcome (GAIS evaluation):
Over 97% rated as "improved,or above by three independent surgeons. No irregularities or lumps observed during follow-up.
3. ACF-derived adipokines contained anti-inflammatory, skin barrier- and lipidbiosynthesis-related components. ACF contained nonviable cells and high levels of collagen I, collagen IV, and laminin. Fibroblasts and procollagen significantly increased in ACF.

Conclusion: ACF filler is an innovative intradermal approach developed to effectively address the thin region. Derived from adipose tissue, ACF is an extracellular matrix collagen scaffold enriched with adipokines, promoting bio-stimulation and tissue regeneration. It offers a sustained-release mechanism that enhances collagen synthesis and protects skin barrier.
Clinically, ACF represents a promising autologous filler for periorbital rejuvenation, improved skin quality, and minimized risks. ACF as a valuable regenerative solution and bring scientific messages for aesthetics and anti-aging treatments.

Декларация COI

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Objectives: This abstract explores the benefits, methodologies, suitable patient identification and impacts of the innovative non-invasive browpexy surgical technique introduced by Dr Mikhail Suturin.

Introduction: Browpexy contributes significantly to enhancing facial aesthetics by revitalising the brow area. However, traditional procedures, primarily reliant on skin excision, often result in lengthy recovery and potential complications such as scarring and consequential alopecia. With the advancement in non-invasive surgical techniques, the field of plastic surgery is undergoing a transformation, offering patients an efficient alternative shortening recovery time and improving cosmetic and long-term outcomes.

Materials / method: A clinical study was undertaken to examine the outcomes and potential complications of Non-invasive browpexy techniques. The medical records of 115 patients have been analysed, comprising 103 women and 12 men aged 25-71 years who had the procedure between December 2021 and November 2024. Follow-up periods ranged from 1.5 to 25 months. The browpexy techniques involved skin fixation, orbicularis oculi muscle and fascia fixation through several micro punch entry points without additional skin excision. Skin folds appearing post-procedure around the entry points smoothed out within two to six week

Results: Non-invasive browpexy has proven effective for improving brow position and rejuvenating appearance. Benefits include no scarring, quick recovery, and natural looking outcomes. This study focused on the efficacy and safety of the procedure, patient satisfaction. Complications included infection (1.2%), bleeding (1.3%), swelling (21.3%) and suture extrusion (4.7%). Measurements of facial dimensions, patient complaints demonstrated that 92.1% of patients yielded positive cosmetic outcomes. When comparing pre/postoperative photographs, 95.2% of patients achieved positive cosmetic results.

Conclusion: Non-invasive browpexy technique developed by Dr. Mikhail Suturin offers a viable alternative to traditional surgical procedures, giving austhetic surgeons a safe and effective method for brow rejuvenation. It has yielded positive results, high patient satisfaction levels, and significant improvements in facial aesthetics. Continued exploration of advancements and innovations in non-invasive browpexy will enable plastic surgeons to improve their techniques and achieve optimal patient results.

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