Objectives: Facial pores are the result of high sebum excretion, decreased elasticity
around pores, and increased hair follicle volume. Conventional treatment options such as topical retinoids, chemical peels, oral anti-androgens, and laser devices have shown mixed results, especially when treating large pores. In this study, the use of exosomes and Botulinum Toxin type A (BTXA) was explored to treat large facial pores.
Materials / method: Subjects with large facial pores were selected for this study and treated in the following sequence. On day 1, the subjects were treated using air dissection and micro-droplet Botulinum Toxin type A. After one week, the exosome was applied to the treatment area using a meso roller. Two weeks later, another round of air dissection and micro-droplet BTXA injection was followed by the exosome application the following week. The subjects were followed up 3 weeks and 6 weeks after day 1 to assess the pore size, depth, and skin roughness using QuantifiCare 3D Lifeviz.
Results: Improvements in pore size and depth, especially for small and medium-sized
pores were recorded during the first follow-up on week 3. After 6 weeks, significant
improvements to pore size and depth were recorded, including large pores. Assessment using QuantifiCare 3D Lifeviz showed improvements in the subject’s skin roughness throughout the follow-up sessions.
Conclusion: Conventional treatments for facial pores have shown mixed results when
used for the treatment of large facial pores. In this study, the use of exosomes and
Botulinum Toxin type A has been demonstrated to be effective in the treatment of large facial pores.
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