Objectives: We intended to find out if Laser treatments, ablative and non-ablative as monotherapy or in combination can represent a meaningful treatment options in selected cases.
Introduction: With a clear increase in the incidence and a continuously earlier onset, the
treatment options for localized resectionable basal cell carcinoma
include micrographically controlled surgery, simple excision, curettage, laser ablation,
cryosurgery, imiquimod, 5-fluorouracil, photodynamic treatment and radiotherapy.
Nonsurgical treatment options are more suited for cases in which surgical procedures lead to disfigurement or functional impairments or for patients with a high surgical risk. Laser treatment, ablative and non-ablative as monotherapy or in combination can represent a meaningful tre
Materials / method: IN pub med and and multiple journals we searched for the use of lasers in NMSC , esp. BCC, their paramenters and results.
Results: Laser ablation with Er:YAG and CO2 lasers continues to be of interest as a potentially less invasive alternative to surgery for the treatment of low-risk superficial and nodular subtypes of BCCs. The lack of histopathological confirmation has been a limitation but a reflectance confocal microscopy (RCM) imaging-guided approach offers cellular-level histopathology-like feedback directly on the patient.
Ablative fractional lasers (AFXL) enhance uptake of topical therapeutics and the concept of fractional laser-assisted drug delivery has now been taken into clinical practice using 5 FU, Imiquimod
Conclusion: In recent years there has been an increase in evidence about the effects of laser treatment of basal cell carcinoma; nevertheless, further studies with a high level of evidence are necessary.
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