摘要

Objectives: The histological results after treatment of Melasma with phenol peeling (Hetter's formulas) are described. The objective of this class is to demonstrate the histological differences achieved in a patient with Melasma treated with phenol peeling. We present the results of phenol peeling after two days, one month and three months of follow-up. We can observe in the results the decrease in melanin, the thickening of the epidermis and the decrease in elastosis, among others. We follow patients whose results are maintained for 2 years. Introduction: Melasma is a chronic dyschromia characterized by brownish spots on the face of young women with a high skin type. Melasma shares histological changes with photoaged skin, such as: elastosis, degeneration of the basement membrane and vascular changes. Melasma treatment is a challenge for dermatologists. Phenol peeling is a deep peeling, which causes necrosis followed by inflammation, scarring and remodeling of the skin. Melasma treatment with phenol peeling can be a good option. Materials / method: Women with chronic Melasma between 20 and 65 years old without hormonal changes in whom a biopsy was performed on an exposed area before and after peeling. Application of phenol peeling with the following formulation: - Water 5.5 ml - Soap 0.5 ml - Stock solution (1 ml of croton oil and 24 ml of phenol 88%) 1 ml - Phenol 88% 3 ml The final solution has 35% phenol and 0.8% croton oil (Hetter's formula) Results: The exam results are presented during the class: - Post phenol 2 days - Post phenol 1 month - Post phenol 3 months Conclusion: Phenol peeling with Hetter's formula 0.8% croton was safe and effective for treating Melasma.