摘要

Objectives: This study aims to demonstrate the feasibility and efficacy of autologous micrograft therapy as a minimally invasive treatment for androgenetic alopecia. Through a series of ten cases, we seek to illustrate indications, outcomes, potential complications, and real-world challenges of its application in a dermatological hair treatment center. Introduction: Androgenetic alopecia is a chronic hair disorder that often requires long-term management. While home-based clinical treatment is fundamental, additional minimally invasive procedures can enhance patients' quality of life, especially those with mild to moderate cases unwilling or unable to undergo surgical transplantation or frequent office visits. We propose evaluating the viability of autologous micrograft therapy performed under local anesthesia on an outpatient basis. Materials / method: The technique involves extracting small skin fragments under local anesthesia from the occipital region of the patient. Following mechanical processing, a solution containing mesenchymal cells and growth factors is applied to the desired areas of the scalp using a 4mm needle, akin to intradermal injections. Ten cases will be presented to showcase indications, results, potential complications, and real-world challenges. Results: Our study demonstrates the feasibility and efficacy of autologous micrograft therapy for androgenetic alopecia. Significant improvements in hair density and quality were observed in the treated areas, with minimal complications reported. These findings suggest that autologous micrograft therapy could be a valuable option for individuals with unsatisfactory responses to conventional treatments, those averse to surgical intervention, or those preferring less frequent treatments. Conclusion: In conclusion, autologous micrograft therapy presents a promising avenue for the treatment of androgenetic alopecia, offering a minimally invasive alternative for patients with mild to moderate cases who may not be suitable candidates for surgical intervention or frequent office visits. Our study demonstrates its feasibility and efficacy in improving hair density and quality, with minimal complications. This approach fills a gap in the treatment landscape, providing individuals with unsatisfactory responses to conventional therapies an alternative option for hair restoration.