摘要

Objectives: PDT stands out as one of the most effective therapeutic protocols licensed for treating actinic keratoses and field cancerization. Beyond its oncological impact, both the epidermal and dermal effects of PDT contribute to the dermal remodeling of photodamaged skin, resulting in significant photorejuvenation. Introduction: "Photoaging, stemming from continuous exposure to ultraviolet (UV) irradiation, leads to the accumulation of DNA damage. Clinically, this manifests as thickened, rough skin with fine lines, coarse wrinkles, mottled pigmentation, elastosis, and precancerous lesions (actinic keratoses). This is the most common skin condition experienced by our patients Materials / method: While conventional PDT requires a photosensitizer and a specific light source, Daylight PDT is a simple yet effective technique that should be widely embraced by dermatologists. Its primary focus is on treating pre-cancerous lesions, with the added benefit of enhancing skin quality. Results: This talk explores various pre-treatment strategies, emphasizing the importance of drug penetration into the stratum corneum. Daylight PDT can be further improved with assisted medication administration, including pre-photosensitizer chemical or mechanical peeling or microneedling (0.25 to 0.50 mm) after photosensitizer, optimizing the results of subsequent aesthetic treatments. And if the patient needs to treat vascular and pigmentary problems, IPL can also be used as a light source, further improving the aesthetic result. Conclusion: We propose initiating the anti-aging treatment protocol with PDT, not only to enhance aesthetic outcomes but also to ensure the prevention and treatment of pre-cancerous lesions. This approach emphasizes the medical aspect in aesthetic treatment.