摘要

Objectives: 1. Polynucleotide, Growth factors, Exosomes, and Biosomes 2. What is their role in the treatment of skin rejuvenation? Case studies 3. What is their role in the treatment of skin hyperpigmentation? Case studies 4. What is their role in the treatment of hair? Case studies Introduction: Regenerative medicine is pivotal in today's aesthetic industry, with patients seeking natural, youthful results. The key question is whether polynucleotides, growth factors, exosomes, and biosomes are essential for skin rejuvenation. Understanding their mechanisms and molecular biology is crucial, as is exploring their role in treating various conditions. Additionally, determining whether a robust exosome containing multiple growth factors is more effective than a targeted subset is vital for optimizing regenerative treatments in aesthetic medicine. Materials / method: A literature review was conducted to evaluate the knowledge exist today about growth factors, exosomes, and biosomes. This knowledge was combined with clinical studies and practical experience from my clinics. Results: In regenerative aesthetic medicine, integrating polynucleotides, growth factors, exosomes, and biosomes is crucial for optimal results. Each has unique advantages and drawbacks, requiring a deep understanding to tailor treatments to individual patients. Polynucleotides enhance the cellular microenvironment, while growth factors stimulate specific functions. Exosomes offer potent stimulation but are unpredictable due to their heterogeneity. Biosomes, an evolution of exosomes, allow synthetic delivery of specific growth factors, enabling precise treatments, such as selectively using TGF-BETA 3. Conclusion: • Employ a diverse range of products for skin regeneration, exercising judiciousness by comprehending the purpose behind each application or injection. Ensure a meticulous match between the chosen product and the specific indication for optimal results. • The future of regenerative aesthetic medicine might lie in biosomes, offering a combination of a targeted subset of growth factors and robust natural stimulation. This innovation enables the simultaneous delivery of both precise and powerful regenerative stimuli.