摘要

目标: After attending this lecture, attendees will be exposed to the latest developments in low dose isotretinoin indications, prescription, dosing, side effects, and clinical result. 介绍: Oral isotretinoin is enjoying new, previously unthinkable revitalization of its role in helping patients improving many skin conditions thanks to significant dose reduction and prescription strategies 材料 / 方法: Pertinent literature research and comparison with 15 years old personal experience 结果: See conclusions 总结: Since its first synthesis in 1955, 13-cis-retinoic acid (Ro-4-3780), universally known as Isotretinoin, the enormous potential of this fat-soluble synthetic retinoid was appreciated by the scientific community. Low dose prescriptions have proven extremely effective in many dermatologic indications reducing side-effects to an absolute minimum and expanding the willingness of patients to accept this therapeutic proposal.