摘要

Objectives: To determine the efficacy of a novel combination of a wide spectrum IPL and non-ablative 1540nm laser for the treatment of Post-inflammatory Erythema. Introduction: Post-inflammatory erythema (PIE) occurs when blood flow is disrupted during the inflammation phase causing damage to the capillaries. This disruption in blood flow may be caused by acne or by inflammatory skin conditions. This damage can lead to red or pink marks on the skin. PIE typically self resolves over time. However, to expedite improvement in appearance, EBDs can improve the appearance of PIE. This case study explores combining the coagulative effect and subsequent dermal and vascular remodeling achieved by 1540nm laser, in synergy with an IPL, to improve PIE. Materials / method: 35 patients, ages 21-43 years, skin phototypes II-V, suffering from PIE as a result of acne were treated with a combined treatment protocol using a wide spectrum IPL (420-950nm) and 1540nm laser. The protocol: IPL applicator, fluence of 8 J/cm2, pulse width of 40 msec. Immediately after, Er:Glass pixel laser at an energy range of 1000kJ-1500mJ/P. 2 passes were performed. Patients received 3 treatments, at treatment intervals of 3-5 weeks. Patient satisfaction and clinical condition were assessed using GAIS. Standardized photographs were taken before treatment and at the 1 month follow up. Results: Patients demonstrated moderate to significant improvement in PIE. Photographic assessment of affected areas saw visible cosmetic improvement in all patients. Results were graded according to the GAIS, an average score of 4 was obtained. All patients were satisfied with their improvement. There were no adverse events reported. Conclusion: The combination of 1540nm non-ablative laser used in synergy with a wide band IPL has not been studied as a treatment for PIE. The synergy of non-ablative laser and light-based technologies to treat PIE resulted in moderate to significant improvement and high patient satisfaction. The coagulative columns and subsequent dermal and vascular remodelling as a result of the 1540nm laser in synergy with IPL, where oxyhemoglobin is the target chromophore, leading to photothermal damage, is thought to provide a very good solution for patients suffering from PIE as a result of acne.