摘要

Objectives: The aim of the study is to confirm the efficacy of the sponge spicules peptides carriers in collagen stimulation, in improving skin hydration reinforcing the skin barrier with both an anti inflammatory and anti oxidant effect on the dermis. Introduction: The Aesthetic medical field is directing towards non invasive procedures with no side effects. The patients are more demanding about regenerative and conservative procedures expecting immediate result with no side effects. Different methods have been used during the last decade to allow a non invasive penetration of the active ingredients into the the skin layers: from the microneedling to lasers nanotechnology and encapsulated peptides. Alle these methods have their limits : the microneedling can damage the skin is painful and has a down time as bruising and redness. The absorption of nano Materials / method: I have used spicules derived from pure natural marine sponge to carry my active ingredients customised on the patient’s conditions. These microscopic spicules penetrate the sublayer of the epidermis maximizing the skin’s absorption of otherwise difficult-to-absorb active ingredients. The spicules are bonded with high functioning peptides delivering them in the deeper layers of the skin. The peptides firmly bounded to the micro needles are released upon reaching the designated skin barrier I have treated 5 patients aged between 20 and 50 years with different skin conditions as acne & wrinkles Results: An immediate mild redness was observed in 3 of the patients with a mild itching sensation lasting for 24 to 48 hours. 3 of the patients have peeled 5 days after the procedure. All the patient were extremely satisfied after already the first session. An immediate improvement of the skin texture have been noticed with 30 % more hydration, 20% of skin density improvement and 50% of improvement of enlarged pores and inflammation for the patients with acne Conclusion: The innovative liquid bio-microneedling is a very promoting technology in aesthetic dermatology and regenerative medicine. The procedure is extremely safe effective has no down time and completely painless. As per the actual expectations of the patients demanding immediate results and safe procedures for rejuvenation, the peptides spicules delivered microneedling results to be one the most promoting technology in non invasive skin rejuvenation and regeneration.